ArticleFolia microbiologica2006
Cerebrospinal-fluid profile in neuroborreliosis and its diagnostic significance.
Article in Folia microbiologica, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.
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Who cites it
5 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.
- The diagnostic accuracy of serological tests for Lyme borreliosis in Europe: a systematic review and meta-analysis.BMC infectious diseases · 2016Pooled it
- Use of the Sysmex XT-4000i hematology analyzer in the differentiation of cerebrospinal fluid cells in children.Journal of clinical laboratory analysis · 2019Article
- Bilateral facial palsy: a form of neuroborreliosis presentation in paediatric age.BMJ case reports · 2013Article
- Cryptococcal meningitis--a follow-up study of a serious clinical entity: quick cytological and microbiological diagnostics using a special staining procedure in cerebrospinal fluid specimens.Folia microbiologica · 2009Article
- Analysis of cerebrospinal fluid cell populations with monoclonal antibodies.Folia microbiologica · 2007Article
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Authors and funding
1 author at 1 institution in 1 country.
Funding
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Abstract
Selected cerebrospinal-fluid (CSF) parameters (intrathecal synthesis of Borrelia-specific antibodies, oligoclonal IgG bands, CSF-to-serum quotient of albumin as a marker of blood-CSF barrier function and cytology) and typical CSF profile in neuroborreliosis were evaluated with the aim of elucidating possible clinical and laboratory similarities of neuroborreliosis (NB) and other neurological diseases (OND). From the cohort of 58 patients (38 diagnosed for NB, 20 with OND) NB patients had positive Borrelia-specific IgG antibodies in 97 % and positive Borrelia-specific IgM antibodies in 55 %; oligoclonal IgG bands were detected in 55%. The blood-CSF barrier was impaired in 89%, positive cytology was detected in 97% of the NB patients. Evaluation of specific intrathecal synthesis improves CSF diagnosis of NB, therefore, a combined CSF analysis has to be considered along with the clinical picture and medical history when formulating the diagnosis of NB.
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Registered trials
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