Evidence map›Paper›PMID 17452509›Full record

ReviewHypertension (Dallas, Tex. : 1979)2007

Is angiotensin II a direct mediator of left ventricular hypertrophy? Time for another look.

Timothy L Reudelhuber, Kenneth E Bernstein, Patrick Delafontaine

Abstract readReview
In one paragraph

Review in Hypertension (Dallas, Tex. : 1979), 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed.

  1. An integrated overview of acute heart failure: a narrative review of pathophysiological mechanisms and contributing factors.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2026
    Review
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  16. Intracardiac intracellular angiotensin system in diabetes.American journal of physiology. Regulatory, integrative and comparative physiology · 2012
    Review
  17. Article
  18. Article
  19. Article
  20. Local angiotensin II aggravates cardiac remodeling in hypertension.American journal of physiology. Heart and circulatory physiology · 2010
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Timothy L ReudelhuberLaboratory of Molecular Biochemistry of Hypertension, Clinical Research Institute of Montreal, Montreal, Quebec, Canada. reudelt@ircm.qc.ca
Kenneth E Bernstein
Patrick Delafontaine

Funding

Insulin-Like Growth Factor-1and AtherosclerosisR01HL070241 · NHLBI · UNIVERSITY OF MISSOURI-COLUMBIA · PI PATRICE DELAFONTAINE · 2003 to 2026
$10.1M
ANGIOTENSIN II, IGF-1 AND SKELETAL MUSCLE ATROPHYR01HL080682 · NHLBI · UNIVERSITY OF MISSOURI-COLUMBIA · PI DELAFONTAINE, PATRICE · 2007 to 2015
$3.3M
TESTIS ACE--FUNCTION AND DEVELOPMENTAL EXPRESSIONR01DK051445 · NIDDK · EMORY UNIVERSITY · PI BERNSTEIN, KENNETH E · 1996 to 2008
$2.5M
RENIN/ANGIOTENSIN SYSTEM AND INJURYR37DK039777 · NIDDK · EMORY UNIVERSITY · PI BERNSTEIN, KENNETH E · 1997 to 2006
$2.4M
RENIN/ANGIOTENSIN SYSTEM AND INJURYR01DK039777 · NIDDK · EMORY UNIVERSITY · PI BERNSTEIN, KENNETH E · 1988 to 2010
$1.3M
NHLBI NIH HHS HL70241NHLBI NIH HHS R01 HL070241NHLBI NIH HHS R01 HL080682NIDDK NIH HHS DK039777NIDDK NIH HHS DK051445NIDDK NIH HHS R01 DK039777NIDDK NIH HHS R01 DK051445NIDDK NIH HHS R37 DK039777
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Angiotensin IIAnimalsBlood PressureHumansHypertensionHypertrophy, Left VentricularMiceMice, TransgenicPromoter Regions, GeneticReceptor, Angiotensin, Type 1Renin-Angiotensin SystemVasoconstrictionVentricular MyosinsAngiotensin IIReceptor, Angiotensin, Type 1Ventricular Myosins

Identifiers

PMID17452509
PMCPMC3227117

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.