Evidence map›Paper›PMID 17452471›Full record

ArticleInfection and immunity2007

Fungicidal monoclonal antibody C7 binds to Candida albicans Als3.

Sonia Brena, Miren J Omaetxebarría, Natalia Elguezabal, Jonathan Cabezas, María D Moragues, José Pontón

Abstract read
In one paragraph

Article in Infection and immunity, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 58 citations in OpenAlex.

  1. Article
  2. Article
  3. Vaccine Strategies for Cryptococcus neoformans.Methods in molecular biology (Clifton, N.J.) · 2024
    Article
  4. Promising immunotherapeutic targets for treating candidiasis.Frontiers in cellular and infection microbiology · 2024
    Review
  5. Review
  6. Review
  7. Article
  8. Review
  9. Review
  10. Article
  11. A Therapeutic Vaccine for Recurrent Vulvovaginal Candidiasis.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2018
    Article
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  13. Review
  14. Review
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  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Sonia BrenaDepartamento de Inmunología, Microbiología y Parasitología, Facultad de Medicina y Odontología, Universidad del País Vasco, Apartado 699, E-48080 Bilbao, Vizcaya, Spain.
Miren J Omaetxebarría
Natalia Elguezabal
Jonathan Cabezas
María D Moragues
José Pontón
University of the Basque Country · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Monoclonal antibody (MAb) C7 reacted with a >200-kDa component from the Candida albicans cell wall identified by matrix-assisted laser desorption ionization-time-of-flight mass spectrometry as Als3. It also bound the recombinant N terminus of Als3. Binding of MAb C7 to Als3 may explain the biological activities exerted by the MAb on C. albicans.

Indexed as

Antibodies, FungalAntibodies, MonoclonalAnimalsCandida albicansCell WallEpithelial CellsEpitope MappingFungal ProteinsMiceMouth MucosaRabbitsRecombinant ProteinsSpectrometry, Mass, Matrix-Assisted Laser Desorption-IonizationALS3 protein, Candida albicansAntibodies, FungalAntibodies, MonoclonalFungal ProteinsRecombinant Proteins

Identifiers

PMID17452471
PMCPMC1932956
OpenAlexW2119384644

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.