ArticleWorld journal of gastroenterology2007
Molecularly defined adult-type hypolactasia among working age people with reference to milk consumption and gastrointestinal symptoms.
Article in World journal of gastroenterology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed.
- Should milk-specific IgE antibodies be measured in adults in primary care?Scandinavian journal of primary health care · 2008Trial
- Correlation of G/A -22018 single-nucleotide polymorphism with lactase activity and its usefulness in improving the diagnosis of adult-type hypolactasia among North Indian children.Genes & nutrition · 2013Article
- Evaluation of a genetic test for diagnose of primary hypolactasia in northeast of iran (khorasan).Iranian journal of basic medical sciences · 2012Article
- Lactase non-persistent genotype influences milk consumption and gastrointestinal symptoms in Northern Russians.BMC gastroenterology · 2011Article
- Polymorphism in the oxytocin promoter region in patients with lactase non-persistence is not related to symptoms.BMC gastroenterology · 2009Article
- Milk protein IgG and IgA: the association with milk-induced gastrointestinal symptoms in adults.World journal of gastroenterology · 2009Article
- The T/G 13915 variant upstream of the lactase gene (LCT) is the founder allele of lactase persistence in an urban Saudi population.Journal of medical genetics · 2007Article
- Lactase non-persistence and milk consumption in Estonia.World journal of gastroenterology · 2006Article
- The association between adult-type hypolactasia and symptoms of functional dyspepsia.Genetics and molecular biologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo study milk consumption and subjective milk-related symptoms in adults genotyped for adult-type hypolactasia.
methodsA total of 1900 Finnish adults were genotyped for the C/T(-13910) variant of adult-type hypolactasia and filled in a structured questionnaire concerning milk consumption and gastrointestinal problems.
resultsThe C/C(-13910) genotype of adult-type hypolactasia was present in 18% of the study population. The prevalence of the C/C(-13910) genotype was higher among subjects who were undergoing investigations because of abdominal symptoms (24%, P < 0.05). Those with the C/C(-13910) genotype drank less milk than subjects with either the C/T(-13910) or the T/T(-13910) genotype of lactase persistence (18% vs 38%; 18% vs 36%, P < 0.01). Subjects with the C/C(-13910) genotype had experienced more gastrointestinal symptoms (84%) during the preceding three-month period than those with the C/T(-13910) (79%, P < 0.05) or the T/T(-13910) genotype (78 %, P < 0.05). Only 9% (29/338) of the subjects with the C/C(-13910) genotype consumed milk and reported no symptoms from it.
conclusionGastrointestinal symptoms are more common among adults with the C/C(-13910) genotype of adult-type hypolactasia than in those with genotypes of lactase persistence.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.