ArticleImmunogenetics2007
The expanded cattle KIR genes are orthologous to the conserved single-copy KIR3DX1 gene of primates.
Article in Immunogenetics, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed, 61 citations in OpenAlex.
- Bighorn sheep T2T genome assembly reveals differences in immune genes: a potential cause of high morbidity due to respiratory pathogens.bioRxiv : the preprint server for biology · 2025Article
- Remarkably Low KIR and HLA Diversity in Amerindians Reveals Signatures of Strong Purifying Selection Shaping the Centromeric KIR Region.Molecular biology and evolution · 2022Article
- The Genomic Organization of theFrontiers in immunology · 2021Review
- The Genetic Mechanisms Driving Diversification of theFrontiers in immunology · 2020Review
- The Structure, Evolution, and Gene Expression Within the Caprine Leukocyte Receptor Complex.Frontiers in immunology · 2019Article
- The unique evolution of the pig LRC, a single KIR but expansion of LILR and a novel Ig receptor family.Immunogenetics · 2018Article
- Nomenclature for the KIR of non-human species.Immunogenetics · 2018Article
- NK cells produce high levels of IL-10 early after allogeneic stem cell transplantation and suppress development of acute GVHD.European journal of immunology · 2018Article
- The evolution of the natural killer complex; a comparison between mammals using new high-quality genome assemblies and targeted annotation.Immunogenetics · 2017Article
- The evolution of natural killer cell receptors.Immunogenetics · 2016Review
- Co-evolution of MHC class I and variable NK cell receptors in placental mammals.Immunological reviews · 2015Review
- Cattle NK Cell Heterogeneity and the Influence of MHC Class I.Journal of immunology (Baltimore, Md. : 1950) · 2015Article
- Definition of the cattle killer cell Ig-like receptor gene family: comparison with aurochs and human counterparts.Journal of immunology (Baltimore, Md. : 1950) · 2014Article
- Bimodal evolution of the killer cell Ig-like receptor (KIR) family in New World primates.Immunogenetics · 2013Article
- Variable NK cell receptors and their MHC class I ligands in immunity, reproduction and human evolution.Nature reviews. Immunology · 2013Review
- IPD--the Immuno Polymorphism Database.Nucleic acids research · 2013Article
- Analysis of the expression of KIR and HLA-Cw in a Northeast Han population.Experimental and therapeutic medicine · 2013Article
- Article
- Constraints on haplotype structure and variable gene frequencies suggest a functional hierarchy within cattle MHC class I.Immunogenetics · 2012Article
- Human-specific evolution of killer cell immunoglobulin-like receptor recognition of major histocompatibility complex class I molecules.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2012Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
Cattle are the only non-primate species for which expansion of the killer cell immunoglobulin-like receptor (KIR) genes has been reported. We analyzed cattle KIR sequences to determine their relationship to the two divergent lineages of primate KIR: one comprising the KIR3DX1 gene of unknown function, the second comprising all other primate KIR genes, which encode variable major histocompatibility complex class I receptors. Phylogenetics and analysis of repetitive elements shows that cattle KIR subdivide into the same two lineages as primate KIR. Unlike the primates, the lineage of variable and likely functional cattle KIR corresponds to the KIR3DX1 lineage of primate KIR, whereas the variable lineage of primate KIR is represented in cattle by one KIR gene and a related gene fragment.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.