ArticleThe Plant cell2007
MONODEHYROASCORBATE REDUCTASE4 is required for seed storage oil hydrolysis and postgerminative growth in Arabidopsis.
Article in The Plant cell, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
59 citing papers in PubMed, 129 citations in OpenAlex.
- A redox-regulated RCC1-like protein controls catalase activity in Arabidopsis.Nature communications · 2026Article
- Transcriptome Profiling Reveals the Response of Seed Germination ofPlants (Basel, Switzerland) · 2024Article
- The ascorbate-glutathione cycle coming of age.Journal of experimental botany · 2024Review
- KiwifruitInternational journal of molecular sciences · 2023Article
- Rice lipases: a conundrum in rice bran stabilization: a review on their impact and biotechnological interventions.Physiology and molecular biology of plants : an international journal of functional plant biology · 2023Review
- Genome-Wide Identification and Comparative Transcriptome Methods RevealInternational journal of molecular sciences · 2023Article
- Snapshot of four mature quinoa (Physiology and molecular biology of plants : an international journal of functional plant biology · 2023Article
- Proteomic Analysis Reveals a Critical Role of the Glycosyl Hydrolase 17 Protein inInternational journal of molecular sciences · 2023Article
- Ascorbate-Glutathione Cycle Genes Families in Euphorbiaceae: Characterization and Evolutionary Analysis.Biology · 2022Article
- Characterization and analysis of the promoter region of monodehydroascorbate reductase 4 (CpMDAR4) in papaya.Plant reproduction · 2022Article
- Peroxisome-Mediated Reactive Oxygen Species Signals Modulate Programmed Cell Death in Plants.International journal of molecular sciences · 2022Review
- Spatially patterned hydrogen peroxide orchestrates stomatal development in Arabidopsis.Nature communications · 2022Article
- Reactive Oxygen Species, Antioxidant Responses and Implications from a Microbial Modulation Perspective.Biology · 2022Review
- Specificity of HCellular & molecular biology letters · 2022Review
- CSN improves seed vigor of aged sunflower seeds by regulating the fatty acid, glycometabolism, and abscisic acid metabolism.Journal of advanced research · 2021Article
- Genomic characterization of a rare Carica papaya X chromosome mutant reveals a candidate monodehydroascorbate reductase 4 gene involved in all-hermaphrodite phenomenon.Molecular genetics and genomics : MGG · 2021Article
- Distribution and Functions of Monodehydroascorbate Reductases in Plants: Comprehensive Reverse Genetic Analysis ofAntioxidants (Basel, Switzerland) · 2021Article
- Peroxisomes as redox-signaling nodes in intracellular communication and stress responses.Plant physiology · 2021Review
- Genome-Wide Analysis of MDHAR Gene Family in Four Cotton Species Provides Insights into Fiber Development via Regulating AsA Redox Homeostasis.Plants (Basel, Switzerland) · 2021Article
- High Drying Temperature Accelerates Sunflower Seed Deterioration by Regulating the Fatty Acid Metabolism, Glycometabolism, and Abscisic Acid/Gibberellin Balance.Frontiers in plant science · 2021Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
Hydrogen peroxide is a major by-product of peroxisomal metabolism and has the potential to cause critical oxidative damage. In all eukaryotes, catalase is thought to be instrumental in removing this H(2)O(2). However, plants also contain a peroxisomal membrane-associated ascorbate-dependent electron transfer system, using ascorbate peroxidase and monodehydroascorbate reductase (MDAR). Here, I report that the conditional seedling-lethal sugar-dependent2 mutant of Arabidopsis thaliana is deficient in the peroxisomal membrane isoform of MDAR (MDAR4). Following germination, Arabidopsis seeds rely on storage oil breakdown to supply carbon skeletons and energy for early seedling growth, and massive amounts of H(2)O(2) are generated within the peroxisome as a by-product of fatty acid beta-oxidation. My data suggest that the membrane-bound MDAR4 component of the ascorbate-dependent electron transfer system is necessary to detoxify H(2)O(2), which escapes the peroxisome. This function appears to be critical to protect oil bodies that are in close proximity to peroxisomes from incurring oxidative damage, which otherwise inactivates the triacylglycerol lipase SUGAR-DEPENDENT1 and cuts off the supply of carbon for seedling establishment.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.