ArticleJournal of bacteriology2007
Translational regulation of the Escherichia coli stress factor RpoS: a role for SsrA and Lon.
Article in Journal of bacteriology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 49 citations in OpenAlex.
- Article
- RpoS and the bacterial general stress response.Microbiology and molecular biology reviews : MMBR · 2024Review
- RNA-seq reveals multifaceted gene expression response to Fab production in Escherichia coli fed-batch processes with particular focus on ribosome stalling.Microbial cell factories · 2024Article
- Convergent genetic adaptation ofFrontiers in molecular biosciences · 2024Article
- Antibiotic tolerance is associated with a broad and complex transcriptional response in E. coli.Scientific reports · 2021Article
- Comparative genomic identification and characterization of npcRNA homologs inJournal of biosciences · 2021Article
- Trans-Acting Small RNAs and Their Effects on Gene Expression inEcoSal Plus · 2020Review
- Trouble is coming: Signaling pathways that regulate general stress responses in bacteria.The Journal of biological chemistry · 2019Review
- In silico 'fishing' using known small regulatory RNA (sRNA) candidates as the decoy from Escherichia coli, Salmonella typhi and Salmonella typhimurium manifested 14 novel sRNA candidates in the orthologous region of Proteus mirabilis.Molecular biology reports · 2018Article
- Endogenous rRNA Sequence Variation Can Regulate Stress Response Gene Expression and Phenotype.Cell reports · 2018Article
- Critical role for a promoter discriminator in RpoS control of virulence in Edwardsiella piscicida.PLoS pathogens · 2018Article
- The i6A37 tRNA modification is essential for proper decoding of UUX-Leucine codons during rpoS and iraP translation.RNA (New York, N.Y.) · 2016Article
- Genetic Selection of Peptide Aptamers That Interact and Inhibit Both Small Protein B and Alternative Ribosome-Rescue Factor A of Aeromonas veronii C4.Frontiers in microbiology · 2016Article
- Absence of tmRNA Has a Protective Effect against Fluoroquinolones inFrontiers in microbiology · 2016Article
- The MiaA tRNA modification enzyme is necessary for robust RpoS expression in Escherichia coli.Journal of bacteriology · 2014Article
- tmRNA-mediated trans-translation as the major ribosome rescue system in a bacterial cell.Frontiers in genetics · 2014Review
- Mechanism of trans-translation revealed by in vitro studies.Frontiers in microbiology · 2014Review
- The transfer-messenger RNA-small protein B system plays a role in avian pathogenic Escherichia coli pathogenicity.Journal of bacteriology · 2013Article
- Article
- Competition among Hfq-binding small RNAs in Escherichia coli.Molecular microbiology · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 2 countries.
Funding
Abstract
Escherichia coli cell viability during starvation is strongly dependent on the expression of the rpoS gene, encoding the RpoS sigma subunit of RNA polymerase. RpoS abundance has been reported to be regulated at many levels, including transcription initiation, translation, and protein stability. The regulatory RNA SsrA (or tmRNA) has both tRNA and mRNA activities, relieving ribosome stalling and cotranslationally tagging proteins. We report here that SsrA is needed for the correct high-level translation of RpoS. The ATP-dependent protease Lon was also found to negatively affect RpoS translation, but only at low temperature. We suggest that SsrA may indirectly improve RpoS translation by limiting ribosome stalling and depletion of some component of the translation machinery.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.