Evidence map›Paper›PMID 17449271›Full record

ArticleCytokine2007

Effect of storage temperatures on the stability of cytokines in cervical mucous.

Gitika Panicker, Kristi S Meadows, Daisy R Lee, Rosane Nisenbaum, Elizabeth R Unger

Abstract readEvaluation Study
In one paragraph

Article in Cytokine, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Cytokines in Bladder Pain Syndrome: A Review of the Literature.International urogynecology journal · 2024
    Review
  2. Cytokines: From Clinical Significance to Quantification.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Effects of storage conditions on the stability of serum CD163, NGAL, HMGB1 and MIP2.International journal of clinical and experimental pathology · 2015
    Article
  9. Cytokines as biomarkers in rheumatoid arthritis.Mediators of inflammation · 2014
    Review
  10. Article
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Gitika PanickerCenters for Disease Control and Prevention, Division of Viral and Rickettsial Diseases, Viral Exanthems and Herpesvirus Branch, Atlanta, GA 30333, USA. dhv1@cdc.gov
Kristi S Meadows
Daisy R Lee
Rosane Nisenbaum
Elizabeth R Unger

Funding

HUMAN STUDIES OF DIET AND NUTRITIONZ01CN000101 · CN · CANCER PREVENTION AND CONTROL · PI TAYLOR, PHILIP · 1985 to 2004
–
Intramural NIH HHS Z01 CN000101NCI NIH HHS Y01 CN000101NCI NIH HHS Y1 CN010101
6 · The paper itself

Abstract

Cytokines have progressively come to serve as indicators for the presence or severity of a disease. But accurate measurement of cytokine levels can be deterred by lack of proper handling and storage of the samples. In this study, we attempted to measure the effect of snap-freezing and refrigeration at the time of collection on cervical mucous. Luminex analyses of the frozen and refrigerated pairs exhibited no significant differences in levels for 7 out of the 10 cytokines measured simultaneously. The cytokines TNF-alpha, IFN-gamma and IL-1beta, were significantly different between the pairs with the refrigerated samples showing higher levels for each of these cytokines. The results suggest that refrigeration of mucous samples immediately after collection would allow for better conservation of the cytokines in cervical mucous.

Indexed as

FreezingTemperatureCervix MucusCytokinesFemaleHumansPreservation, BiologicalProtein Array AnalysisCytokines

Identifiers

PMID17449271
PMCPMC1945112

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.