ReviewCurrent allergy and asthma reports2007
The potential of Mycobacterium to protect against allergy and asthma.
Review in Current allergy and asthma reports, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed, 26 citations in OpenAlex.
- Environmental exposures associated with atopy in a rural community in Gwanda district, Zimbabwe: a cross-sectional study.Frontiers in public health · 2024Article
- A feasibility study to assess Imbrasia belina (mopane worm) sensitisation and related respiratory health outcomes in a rural community in Gwanda district, Zimbabwe.Pilot and feasibility studies · 2021Article
- Assessing the nature of asthma in African epidemiological studies: a scoping review protocol.Systematic reviews · 2020Article
- Vaccine Potential of Mycobacterial Antigens against Asthma.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2020Review
- Article
- Regulatory effect of microRNA-135a on the Th1/Th2 imbalance in a murine model of allergic rhinitis.Experimental and therapeutic medicine · 2014Article
- The effect of natural adjuvants on pathological changes in sensitized Guinea pig lungs.Iranian Red Crescent medical journal · 2014Article
- Toxoplasma gondii infection blocks the development of allergic airway inflammation in BALB/c mice.Clinical and experimental immunology · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The increase in the global incidence of atopic disease and asthma during the past few decades has been ascribed to environmental factors, including the reduction in exposure to serious infections. The hypothetical framework to explain the inverse relationship between infections and atopic disease and asthma has been called the "hygiene hypothesis." Animal and experimental models have identified Mycobacteria as important potential candidates in the hygiene hypothesis by demonstrating that exposure to Mycobacteria or mycobacterial proteins led to subsequent reduction in different atopic manifestations. Although there are epidemiological studies in support, they have not always been consistent. In this review we appraise epidemiologic evidence on the inverse relationship between mycobacterial exposure and atopic disease, explore the immunological mechanisms involved and evidence that this effect may be dose-dependent, and discuss the challenges facing the use of Mycobacteria as vaccine for prevention of atopic disease.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.