SynthesisInternational journal of colorectal disease2007
Malignant neoplasms of the appendix.
Synthesis in International journal of colorectal disease, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 2 of them syntheses that pooled it.
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Who cites it
44 citing papers in PubMed, 2 syntheses or guidelines pooled it, 108 citations in OpenAlex.
- Swedish national guidelines for diagnosis and management of acute appendicitis in adults and children.BJS open · 2025Guideline
- Acute appendicitis, inflammatory appendiceal mass and the risk of a hidden malignant tumor: a systematic review of the literature.World journal of emergency surgery : WJES · 2017Pooled it
- Defining a 'cells to society' research framework for appendiceal tumours.Nature reviews. Cancer · 2025Review
- Molecular and Clinicopathologic Impact of GNAS Variants Across Solid Tumors.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2024Article
- Article
- Review
- Parasitological and histopathological features of appendectomy specimens in Fars Province, southern Iran: a retrospective study.Annals of medicine and surgery (2012) · 2023Article
- Molecular Classification of Appendiceal Adenocarcinoma.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2023Article
- Neoplasms of the appendix: Single institution and ten-year experiences results.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2022Article
- Article
- Article
- Appendicitis with submucosal fecalith mimicking a submucosal tumor: a case report.Surgical case reports · 2021Article
- Appendicular neoplasms and consequences in patients undergoing surgery for suspected acute appendicitis.International journal of colorectal disease · 2020Observational
- Synchronous primary adenocarcinoma of the appendix and colon: Case report and literature review.International journal of surgery case reports · 2020Article
- Typical carcinoids, goblet cell carcinoids, mixed adenoneuroendocrine carcinomas, neuroendocrine carcinomas and adenocarcinomas of the appendix: a comparative analysis of survival profile and predictors.Journal of gastrointestinal oncology · 2019Article
- Appendiceal carcinoma associated with microsatellite instability.Molecular and clinical oncology · 2018Article
- Appendiceal diverticulosis: a harbinger of underlying primary appendiceal adenocarcinoma?Journal of gastrointestinal oncology · 2018Article
- Adenocarcinoma mimicking appendicular lump: a diagnostic dilemma-a case report.World journal of surgical oncology · 2016Article
- Contrast-enhanced ultrasound improves accurate identification of appendiceal mucinous adenocarcinoma in an old patient: A case report.Medicine · 2016Article
- Appendix adenocarcinoma in an elderly patient from a nursing home.Ulusal cerrahi dergisi · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAppendiceal neoplasms, first described in 1882, are still rare, with pre-operative diagnosis invariably difficult. We present our 10-year experience of these lesions with a review of current epidemiology, pathology and treatment modalities. MATERIALS AND
methodsA retrospective histopathological review of all appendicectomy specimens was completed between April 1994 and December 2003 to identify patients diagnosed with malignant neoplasms. Patient demographics, operative details, histopathology and clinical outcomes were obtained from case notes. A literature search of the PubMed database was then performed using the medical search headings; appendix, tumour, neoplasm and malignancy.
resultsTwenty-two patients (eight men) were identified during the study period, with no age difference between gender (mean age in women 58, range 14-83 vs mean age in men 55, range 16-78). Eleven patients were found to have carcinoid-type tumours, eight patients with adenocarcinomas and three patients with lymphomas. Other appendiceal pathologies were identified after appendicectomies, hemicolectomy and oophorectomy. Mean follow-up was 41 months (range 1-125 months). Fourteen patients were alive at the end of follow-up. Patients with classical carcinoid tumours (CCT) had better outcomes than patients with the goblet cell carcinoid, adenocarcinoma and lymphoma.
conclusionsFrom our own experience and a subsequent review of the literature, we recommend right hemicolectomy as the treatment of choice for all malignant appendiceal neoplasms, except for small CCT less than 2 cm in diameter at the tip of the appendix, with a low proliferative index, without angiolymphatic or mesoappendiceal extension. Further adjuvant therapy should be considered after oncological assessment.
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