ReviewTrends in genetics : TIG2007
Silencing by imprinted noncoding RNAs: is transcription the answer?
Review in Trends in genetics : TIG, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 77 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
77 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Long non-coding RNAs in renal cell carcinoma: A systematic review and clinical implications.Oncotarget · 2017Pooled it
- Long Non-Coding RNAs: Key Regulators of Economic Traits in Livestock From Mechanisms to Breeding Applications.Veterinary medicine and science · 2026Review
- A symphony of signals: the intricate role of lncRNAs in dermatological disorders.Clinical and experimental medicine · 2025Review
- Multiple copy number variants ofFrontiers in plant science · 2025Article
- Transcription regulation by long non-coding RNAs: mechanisms and disease relevance.Nature reviews. Molecular cell biology · 2024Review
- Role of oncogenic long noncoding RNA KCNQ1OT1 in colon cancer.Oncology research · 2024Article
- HOXC10 is significantly overexpressed in colorectal cancer.Biomedical reports · 2020Article
- Long noncoding RNA functionality in imprinted domain regulation.PLoS genetics · 2020Review
- Is imprinting the result of "friendly fire" by the host defense system?PLoS genetics · 2020Review
- Analysis of Survival-Related lncRNA Landscape Identifies A Role for LINC01537 in Energy Metabolism and Lung Cancer Progression.International journal of molecular sciences · 2019Article
- Comprehensive analysis of mRNA-lncRNA co-expression profile revealing crucial role of imprinted gene cluster DLK1-MEG3 in chordoma.Oncotarget · 2017Article
- Exploring the secrets of long noncoding RNAs.International journal of molecular sciences · 2015Review
- A novel antisense long noncoding RNA within the IGF1R gene locus is imprinted in hematopoietic malignancies.Nucleic acids research · 2014Article
- Differentially methylated regions in maternal and paternal uniparental disomy for chromosome 7.Epigenetics · 2014Article
- Human RNAi pathway: crosstalk with organelles and cells.Functional & integrative genomics · 2014Review
- An improved canine genome and a comprehensive catalogue of coding genes and non-coding transcripts.PloS one · 2014Article
- Genome-wide high resolution parental-specific DNA and histone methylation maps uncover patterns of imprinting regulation in maize.Genome research · 2014Article
- Long non-coding RNAs in haematological malignancies.International journal of molecular sciences · 2013Review
- Transgene- and locus-dependent imprinting reveals allele-specific chromosome conformations.Proceedings of the National Academy of Sciences of the United States of America · 2013Article
- Gene regulation by the act of long non-coding RNA transcription.BMC biology · 2013Review
17 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Non-coding RNAs (ncRNAs) with gene regulatory functions are starting to be seen as a common feature of mammalian gene regulation with the discovery that most of the transcriptome is ncRNA. The prototype has long been the Xist ncRNA, which induces X-chromosome inactivation in female cells. However, a new paradigm is emerging--the silencing of imprinted gene clusters by long ncRNAs. Here, we review models by which imprinted ncRNAs could function. We argue that an Xist-like model is only one of many possible solutions and that imprinted ncRNAs could provide the better model for understanding the function of the new class of ncRNAs associated with non-imprinted mammalian genes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.