ReviewNeuroscience and biobehavioral reviews2007
Neurobiological mechanisms for the regulation of mammalian sleep-wake behavior: reinterpretation of historical evidence and inclusion of contemporary cellular and molecular evidence.
Review in Neuroscience and biobehavioral reviews, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 107 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
107 citing papers in PubMed.
- Neurophysiologic assessment of brain maturation after an 8-week trial of skin-to-skin contact on preterm infants.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2009Trial
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- The use ofFrontiers in cell and developmental biology · 2026Review
- Relationship Between Sleep Duration and Psychosocial Well-Being in Healthcare Personnel: Identification of Predictors and Vulnerability Patterns.Behavioral sciences (Basel, Switzerland) · 2025Article
- A critical appraisal of tools for delivery room assessment of the newborn infant.Pediatric research · 2024Review
- Elevated pain sensitivity is associated with reduced rapid eye movement (REM) sleep in females with comorbid temporomandibular disorder and insomnia.Pain medicine (Malden, Mass.) · 2024Article
- Abnormal Topological Organization of Structural Covariance Networks in Patients with Temporal Lobe Epilepsy Comorbid Sleep Disorder.Brain sciences · 2023Article
- Neurological Insights into Sleep Disorders in Parkinson's Disease.Brain sciences · 2023Review
- Cognitive neuroscience perspective on memory: overview and summary.Frontiers in human neuroscience · 2023Article
- General anesthesia and sleep: like and unlike.Anesthesia and pain medicine · 2022Review
- Discharge characteristics of neurons of nucleus reuniens across sleep-wake states in the behaving rat.Behavioural brain research · 2021Article
- Article
- No cognitive processing in the unconscious, anesthetic-like, state of sleep.The Journal of comparative neurology · 2021Review
- Model-based analysis and forecast of sleep-wake regulatory dynamics: Tools and applications to data.Chaos (Woodbury, N.Y.) · 2021Article
- Article
- Acute and Chronic Insomnia: What Has Time and/or Hyperarousal Got to Do with It?Brain sciences · 2020Article
- State-dependent brainstem ensemble dynamics and their interactions with hippocampus across sleep states.eLife · 2020Article
- Fronto-central slow cortical activity is attenuated during phasic events in rapid eye movement sleep at full-term birth.Early human development · 2019Article
- Chronotherapies for Parkinson's disease.Progress in neurobiology · 2019Review
- Local Sleep Oscillations: Implications for Memory Consolidation.Frontiers in neuroscience · 2019Article
47 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
At its most basic level, the function of mammalian sleep can be described as a restorative process of the brain and body; recently, however, progressive research has revealed a host of vital functions to which sleep is essential. Although many excellent reviews on sleep behavior have been published, none have incorporated contemporary studies examining the molecular mechanisms that govern the various stages of sleep. Utilizing a holistic approach, this review is focused on the basic mechanisms involved in the transition from wakefulness, initiation of sleep and the subsequent generation of slow-wave sleep and rapid eye movement (REM) sleep. Additionally, using recent molecular studies and experimental evidence that provides a direct link to sleep as a behavior, we have developed a new model, the cellular-molecular-network model, explaining the mechanisms responsible for regulating REM sleep. By analyzing the fundamental neurobiological mechanisms responsible for the generation and maintenance of sleep-wake behavior in mammals, we intend to provide a broader understanding of our present knowledge in the field of sleep research.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.