ArticleVirology2007
Recombination in feline immunodeficiency virus genomes from naturally infected cougars.
Article in Virology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed.
- Altered lentiviral infection dynamics follow genetic rescue of the Florida panther.Proceedings. Biological sciences · 2019Article
- New World feline APOBEC3 potently controls inter-genus lentiviral transmission.Retrovirology · 2018Article
- Article
- Evolution of puma lentivirus in bobcats (Lynx rufus) and mountain lions (Puma concolor) in North America.Journal of virology · 2014Article
- Isolation and identification of a novel rabies virus lineage in China with natural recombinant nucleoprotein gene.PloS one · 2012Article
- Intragenic recombination as a mechanism of genetic diversity in bluetongue virus.Journal of virology · 2010Article
- The effect of vaccination on the evolution and population dynamics of avian paramyxovirus-1.PLoS pathogens · 2010Article
- The secondary structure of the 5' end of the FIV genome reveals a long-range interaction between R/U5 and gag sequences, and a large, stable stem-loop.RNA (New York, N.Y.) · 2008Article
- Evolution of the long terminal repeat and accessory genes of feline immunodeficiency virus genomes from naturally infected cougars.Virology · 2008Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Recombination contributes significantly to diversity within virus populations and ultimately to viral evolution. Here we use a recently developed statistical test to perform exploratory analysis of recombination in fourteen feline immunodeficiency virus (FIVpco) genomes derived from a wild population of cougars. We use both the global and local Phi statistical test as an overall guide to predict where recombination may have occurred. Further analyses, including similarity plots and phylogenetic incongruence tests, confirmed that three FIVpco lineages were derived from recombinant events. Interestingly, the regions of mosaic origin were clustered in the area encoding lentiviral accessory genes and largely spared the viral structural genes. Because some of the mosaic strains are currently geographically disparate, our data indicate that the dispersal of cougars infected with these strains was preceded by recombination events. These results suggest that recombination has played an important role in the evolution of FIVpco for this wild population of cougars.
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Registered trials
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