Evidence map›Paper›PMID 17444812›Full record

ReviewAnnual review of nutrition2007

Taste receptor genes.

Alexander A Bachmanov, Gary K Beauchamp

Registry-linked trialOpen access · greenAbstract readReview
In one paragraph

Review in Annual review of nutrition, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02859116 (Collection of Gastrointestinal Tissue Samples for the Characterization and ex Vivo Functional Assessment of Chemoreceptors), which is not on this map. Cited by 191 papers.

0numbers the graph read from it
0cells of the map it votes in
191citing papers in PubMed
13.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02859116 completednot on this mapstarted 2016, after this paper: background citation

Collection of Gastrointestinal Tissue Samples for the Characterization and ex Vivo Functional Assessment of Chemoreceptors

TypeobservationalSponsorAdventHealth Translational Research InstituteRan2016 to 2022Enrolled8ConditionsDiabetesArmsCollection of digestive tissues
3 · Its place in the literature

Who cites it

191 citing papers in PubMed, 438 citations in OpenAlex.

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131 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Alexander A BachmanovMonell Chemical Senses Center, Philadelphia, PA 19104, USA. bachmanov@monell.org
Gary K Beauchamp
Monell Chemical Senses Center · US

Funding

MODIFICATION OF SALT TASTER01DC000882 · NIDCD · MONELL CHEMICAL SENSES CENTER · PI BACHMANOV, ALEXANDER A · 1990 to 2013
$4.7M
GENETICS OF ALCOHOL RELATED INGESTIVE BEHAVIORS IN MICER01AA011028 · NIAAA · MONELL CHEMICAL SENSES CENTER · PI BACHMANOV, ALEXANDER A · 1997 to 2007
$1.5M
NIAAA NIH HHS R01 AA011028NIAAA NIH HHS R01 AA 11028NIDCD NIH HHS R01 DC000882NIDCD NIH HHS R01 DC 00882
6 · The paper itself

Abstract

In the past several years, tremendous progress has been achieved with the discovery and characterization of vertebrate taste receptors from the T1R and T2R families, which are involved in recognition of bitter, sweet, and umami taste stimuli. Individual differences in taste, at least in some cases, can be attributed to allelic variants of the T1R and T2R genes. Progress with understanding how T1R and T2R receptors interact with taste stimuli and with identifying their patterns of expression in taste cells sheds light on coding of taste information by the nervous system. Candidate mechanisms for detection of salts, acids, fat, complex carbohydrates, and water have also been proposed, but further studies are needed to prove their identity.

Indexed as

AnimalsHumansMiceNutritional Physiological PhenomenaReceptors, G-Protein-CoupledSignal TransductionTasteTaste Receptors, Type 2Receptors, G-Protein-Coupledtaste receptors, type 1Taste Receptors, Type 2

Identifiers

PMID17444812
PMCPMC2721271
OpenAlexW2147945544

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.