SynthesisThe Cochrane database of systematic reviews2007
Yizhi capsule for vascular dementia.
Synthesis in The Cochrane database of systematic reviews, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed, 5 syntheses or guidelines pooled it, 16 citations in OpenAlex.
- Cerebrolysin for vascular dementia.The Cochrane database of systematic reviews · 2019Pooled it
- Traditional Chinese herbal medicine for vascular dementia.The Cochrane database of systematic reviews · 2018Pooled it
- Pooled it
- Acupuncture for vascular dementia.The Cochrane database of systematic reviews · 2007Pooled it
- Yizhi capsule for vascular dementia.The Cochrane database of systematic reviews · 2007Pooled it
- The role of phytochemicals in the treatment and prevention of dementia.Drugs & aging · 2011Review
- Evidence from the Cochrane Collaboration for Traditional Chinese Medicine therapies.Journal of alternative and complementary medicine (New York, N.Y.) · 2009Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundVascular dementia (VD) is a syndrome or diagnosis that has different causes and clinical manifestations relating to several different vascular mechanisms and changes in the brain. Some traditional Chinese herbal medicines were developed for treating VD. DH: Yizhi capsule is one such herbal concoction which is reported to improve clinical symptoms significantly. The efficacy and adverse effects of Yizhi capsule need to be reviewed systematically and assessed critically to inform clinical practice and guide the continued search for new treatment regimens.
objectivesTo assess the effectiveness and possible adverse events of 'Yizhi capsule' in treating vascular dementia. SEARCH STRATEGY: The Cochrane Dementia and Cognitive Improvement Group's Specialised Register was searched on 18 September 2006 using the terms yi-zhi, "yi zhi" and yizhi. This database contains trial references from major health care databases and ongoing trial database and is up to date. In addition the review authors searched a variety of Chinese databases. SELECTION CRITERIA: Randomised, placebo controlled trials in which patients with vascular dementia were treated with 'Yizhi capsule' were included. DATA COLLECTION AND ANALYSIS: Two authors independently assessed trial quality and extracted data. We telephoned study authors for missing information as to whether treatment allocation was randomised and other methodological details. MAIN
resultsNo studies were found that met the inclusion criteria. We identified nine references to trials which included the term 'Yizhi capsule' in the description of the interventions. Two study authors were contacted by telephone and we discovered that the allocation methods they had used were not actually randomised. Four references were describing the same study. Three studies were excluded because 'positive drugs' were used as a control. AUTHORS'
conclusionsThere is no evidence from randomised controlled trials to support or proscribe against the use of 'Yizhi capsule' as a treatment for vascular dementia.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.