SynthesisThe Cochrane database of systematic reviews2007
Antibiotics for asymptomatic bacteriuria in pregnancy.
Synthesis in The Cochrane database of systematic reviews, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers, 6 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
62 citing papers in PubMed, 6 syntheses or guidelines pooled it, 224 citations in OpenAlex.
- Bed rest in singleton pregnancies for preventing preterm birth.The Cochrane database of systematic reviews · 2015Pooled it
- Routine blood cultures in the management of pyelonephritis in pregnancy for improving outcomes.The Cochrane database of systematic reviews · 2015Pooled it
- Antenatal interventions to reduce preterm birth: an overview of Cochrane Systematic Reviews.BMC research notes · 2014Pooled it
- Interventions for covert bacteriuria in children.The Cochrane database of systematic reviews · 2012Pooled it
- Different antibiotic regimens for treating asymptomatic bacteriuria in pregnancy.The Cochrane database of systematic reviews · 2010Pooled it
- The diagnosis of urinary tract infection: a systematic review.Deutsches Arzteblatt international · 2010 · on this mapPooled it
- The effect of early administration of rectal progesterone in IVF/ICSI twin pregnancies on the preterm birth rate: a randomized trial.BMC pregnancy and childbirth · 2020Trial
- Effect of integrated health promotion intervention and follow up on health issues (clothing way, food habits, urinary habits, sexual behavior habits) related to urinary tract infection among pregnant women. A randomized, clinical trial.Journal of preventive medicine and hygiene · 2020Trial
- Effect of population-based antenatal screening and treatment of genitourinary tract infections on birth outcomes in Sylhet, Bangladesh (MIST): a cluster-randomised clinical trial.The Lancet. Global health · 2019Trial
- Costs and effects of screening and treating low risk women with a singleton pregnancy for asymptomatic bacteriuria, the ASB study.BMC pregnancy and childbirth · 2012Trial
- Antenatal interventions to support newborn survival: updates for the Lives Saved Tool.Journal of global health · 2026Article
- Indicators from training healthcare providers on WHO-recommended best practices in prenatal care in Brazil: A before-and-after study.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026Article
- "Actionable" risk for preterm birth: patterns and prediction in California singleton births 2016-2020.BMC pregnancy and childbirth · 2026Article
- Protecting Kidney Health in the First 1000 Days: The Pediatrician's Role in Safeguarding the Weakest.Diseases (Basel, Switzerland) · 2026Review
- Rethinking urinary tract infections in women with abdominal pain in pregnancy: a prospective case-control study.BMC pregnancy and childbirth · 2026Observational
- Management of acute pyelonephritis in pregnancy in emergency settings: A comparative study of conservative therapy and renal drainage.Journal of education and health promotion · 2026Article
- Bacteriology, antibiotic treatment effect and adverse birth outcomes in pregnant women with and without bacteriuria: a registry study.Infection · 2025Article
- Factors influencing pregnant women's use of antenatal and emergency care services covered by social security: findings from the maternal eCohort in Mexico.BMC pregnancy and childbirth · 2025Observational
- Antimicrobial treatment ameliorates delirium-like phenotypes in a murine model of urinary tract infection.Translational psychiatry · 2025Article
- Vaginal dysbiosis and the potential of vaginal microbiome-directed therapeutics.Frontiers in microbiomes · 2024Review
2 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAsymptomatic bacteriuria occurs in 2% to 10% of pregnancies and, if not treated, up to 30% of mothers will develop acute pyelonephritis. Asymptomatic bacteriuria has been associated with low birthweight and preterm delivery.
objectivesTo assess the effect of antibiotic treatment for asymptomatic bacteriuria on persistent bacteriuria during pregnancy, the development of pyelonephritis and the risk of low birthweight and preterm delivery. SEARCH STRATEGY: We searched the Cochrane Pregnancy and Childbirth Group's Trials Register (January 2007). SELECTION CRITERIA: Randomized trials comparing antibiotic treatment with placebo or no treatment in pregnant women with asymptomatic bacteriuria found on antenatal screening. DATA COLLECTION AND ANALYSIS: We assessed trial quality. MAIN
resultsFourteen studies were included. Overall the study quality was poor. Antibiotic treatment compared to placebo or no treatment was effective in clearing asymptomatic bacteriuria (risk ratio (RR) 0.25, 95% confidence interval (CI) 0.14 to 0.48). The incidence of pyelonephritis was reduced (RR 0.23, 95% CI 0.13 to 0.41). Antibiotic treatment was also associated with a reduction in the incidence of low birthweight babies (RR 0.66, 95% CI 0.49 to 0.89) but a difference in preterm delivery was not seen. AUTHORS'
conclusionsAntibiotic treatment is effective in reducing the risk of pyelonephritis in pregnancy. A reduction in low birthweight is consistent with current theories about the role of infection in adverse pregnancy outcomes, but this association should be interpreted with caution given the poor quality of the included studies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.