ArticleJournal of clinical microbiology2007
High-resolution genetic fingerprinting of European strains of Anaplasma phagocytophilum by use of multilocus variable-number tandem-repeat analysis.
Article in Journal of clinical microbiology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
34 citing papers in PubMed.
- Molecular detection and characterization ofInternational journal for parasitology. Parasites and wildlife · 2025Article
- First molecular detection Anaplasma phagocytophilum in sheep in Brazil.Veterinary research communications · 2025Article
- Vector-Borne Agents in Species of Silky Anteater (Pathogens (Basel, Switzerland) · 2025Article
- Use of Tick Cell Lines in Co-Infection Studies with a Preliminary Study of Co-Culture ofPathogens (Basel, Switzerland) · 2025Article
- Surveillance of tick-borne pathogens present in ticks (Acari: Ixodidae) removed from companion animals in Louisiana, USA.Journal of medical entomology · 2025Article
- Tick-Borne Bacterial Diseases in Europe: Threats to public health.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2024Review
- Preparing Collared Peccary (Pathogens (Basel, Switzerland) · 2024Article
- Host-pathogen associations revealed by genotyping of European strains of Anaplasma phagocytophilum to describe natural endemic cycles.Parasites & vectors · 2023Article
- Molecular evidence of Anaplasma phagocytophilum in olive baboons and vervet monkeys in Kenya.BMC veterinary research · 2021Article
- Molecular Detection of Selected Pathogens with Zoonotic Potential in Deer Keds (Pathogens (Basel, Switzerland) · 2021Article
- Epidemiological and Clinicopathological Features ofFrontiers in veterinary science · 2021Review
- The absence of the drhm gene is not a marker for human-pathogenicity in European Anaplasma phagocytophilum strains.Parasites & vectors · 2020Article
- Prevalence and co-infection with tick-borneInternational journal for parasitology. Parasites and wildlife · 2019Article
- Co-circulation of different A. phagocytophilum variants within cattle herds and possible reservoir role for cattle.Parasites & vectors · 2018Article
- Epidemiology, genetic variants and clinical course of natural infections with Anaplasma phagocytophilum in a dairy cattle herd.Parasites & vectors · 2018Article
- Multiple infections ofVeterinary world · 2016Article
- Evaluation of different nested PCRs for detection of Anaplasma phagocytophilum in ruminants and ticks.BMC veterinary research · 2016Article
- Anaplasma marginale and Anaplasma phagocytophilum: Rickettsiales pathogens of veterinary and public health significance.Parasitology research · 2015Review
- Molecular evidence of potential novel spotted fever group rickettsiae, Anaplasma and Ehrlichia species in Amblyomma ticks parasitizing wild snakes.Parasites & vectors · 2015Article
- Opening the black box of Anaplasma phagocytophilum diversity: current situation and future perspectives.Frontiers in cellular and infection microbiology · 2015Review
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
Anaplasma phagocytophilum is a widely distributed tick-borne pathogen of humans, livestock, and companion animals. We used in silico methods to identify 10 variable-number tandem-repeat (VNTR) loci within the genome sequence of the A. phagocytophilum HZ strain and used these data to develop a multilocus VNTR-based typing scheme for the species. Having confirmed the stability of four of the loci in replicates of the A. phagocytophilum strain that had been subjected to different numbers of passages through cell cocultures in vitro, we then used this typing scheme to discriminate between 20 A. phagocytophilum strains of diverse geographical and host provenances. Extensive diversity was found at each of the four loci studied, with total allele numbers ranging from 13 to 18 and Hunter-Gaston discriminatory index values ranging from 0.93 to 0.99. Only 2 of the 20 strains examined shared alleles at all four loci. The discriminatory power of VNTR analysis was found to be greater than that of either partial msp4 or 16S rRNA gene sequence comparison. The extremely high sensitivity of this novel approach to the genetic fingerprinting of A. phagocytophilum strains should serve well in molecular epidemiological studies of infection transmission, particularly when fine-scale strain delineation is required.
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