ArticleOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2007
Prediction of bone loss using biochemical markers of bone turnover.
Article in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
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Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it, 72 citations in OpenAlex.
- Evidence-based guidelines for the use of biochemical markers of bone turnover in the selection and monitoring of bisphosphonate treatment in osteoporosis: a consensus document of the Belgian Bone Club.International journal of clinical practice · 2009Guideline
- Exploring the Relationship of Bone Turnover Markers and Bone Mineral Density in Community-Dwelling Postmenopausal Women.Disease markers · 2021Trial
- Calcium and vitamin D fortified milk reduces bone turnover and improves bone density in postmenopausal women over 1 year.European journal of nutrition · 2018Trial
- Differential effects of calcium- and vitamin D-fortified milk with FOS-inulin compared to regular milk, on bone biomarkers in Chinese pre- and postmenopausal women.European journal of nutrition · 2016Trial
- Longitudinal Change in Bone Density, Geometry, and Estimated Bone Strength in Older Men and Women From The Gambia: Findings From the Gambian Bone and Muscle Aging Study (GamBAS).Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2023Article
- Osteocalcin and Abdominal Aortic Calcification in Hemodialysis Patients: An Observational Cross-Sectional Study.Frontiers in endocrinology · 2021Article
- Changes in bone mineral density over 10 years in patients with early rheumatoid arthritis.RMD open · 2020Observational
- Intradialytic Calcium Kinetics and Cardiovascular Disease in Chronic Hemodialysis Patients.Blood purification · 2020Article
- Magnesium Intake Predicts Bone Turnover in Postmenopausal Black South African Women.Nutrients · 2019Article
- Article
- Muscle strength and regional lean body mass influence on mineral bone health in young male adults.PloS one · 2018Article
- Bone turnover markers predict hip bone loss in elderly European men: results of the European Male Ageing Study (EMAS).Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2015Article
- Serum osteocalcin levels are inversely associated with plasma glucose and body mass index in healthy Chinese women.Acta pharmacologica Sinica · 2014Article
- Reference intervals of bone turnover markers determined by using their curve-fitting valley for adult females in China.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014Article
- Age-related bone turnover markers and osteoporotic risk in native Chinese women.BMC endocrine disorders · 2014Article
- Bisphosphonate drug holiday: choosing appropriate candidates.Current osteoporosis reports · 2013Review
- National Bone Health Alliance Bone Turnover Marker Project: current practices and the need for US harmonization, standardization, and common reference ranges.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2012Article
- Matrix metalloproteinase-13 is required for osteocytic perilacunar remodeling and maintains bone fracture resistance.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2012Article
- Vitamin K-dependent carboxylation of osteocalcin: friend or foe?Advances in nutrition (Bethesda, Md.) · 2012Review
- Polymorphisms in the inflammatory genes CIITA, CLEC16A and IFNG influence BMD, bone loss and fracture in elderly women.PloS one · 2012Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
unlabelledThe association between baseline levels of eleven bone turnover markers and 5-year rate of bone density change was prospectively studied in a population-based sample of 601 75-year-old women. Several bone formation and resorption markers as well as urinary osteocalcin were modestly correlated to rate of bone density change.
introductionPrediction of bone loss by bone turnover markers (BTMs) has been investigated with conflicting results. There is limited information in the elderly.
methodsEleven bone turnover markers were analyzed in 75-year old women in the OPRA study (n = 601) and compared to the 5-year change of areal bone mineral density (aBMD) in seven skeletal regions.
resultsAnnual aBMD change varied between +0.4% (spine) and -2.0% (femoral neck). Significant associations (p < 0.01) were found for four different serum osteocalcins (S-OCs) (standardized regression coefficient -0.20 to -0.22), urinary deoxypyridinoline (-0.19), serum TRACP5b (-0.19), serum CTX-I (-0.21), two of the three urinary osteocalcins (U-OCs) (-0.16) and aBMD change of the leg region (derived from the total body measurement). After adjustment for baseline aBMD, associations were found for all S-OCs (-0.11 to -0.16), two of the three U-OCs (-0.14 to -0.16) and aBMD change at the total hip, and for three of the four S-OCs (-0.14 to -0.15), S-TRACP5b (-0.11), two of the three U-OCs (-0.14 to -0.15) and aBMD change at the femoral neck. There were no significant results concerning aBMD change at the spine.
conclusionThis study indicates that BTMs are correlated with aBMD loss in some skeletal regions in elderly women.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.