ArticlePloS one2007
Divergent evolution among teleost V1r receptor genes.
Article in PloS one, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Article
- Variation in selection constraints on teleost TLRs with emphasis on their repertoire in the Walking catfish, Clarias batrachus.Scientific reports · 2020Article
- Zebrafish olfactory receptors ORAs differentially detect bile acids and bile salts.The Journal of biological chemistry · 2019Article
- Assessing the Genetic Landscape of Animal Behavior.Genetics · 2018Article
- Article
- Article
- Proteomic analyses of courtship pheromones in the redback salamander, Plethodon cinereus.Journal of chemical ecology · 2014Article
- The sea lamprey has a primordial accessory olfactory system.BMC evolutionary biology · 2013Article
- Contrasted evolution of the vomeronasal receptor repertoires in mammals and squamate reptiles.Genome biology and evolution · 2013Article
- Mutually exclusive expression of Gαia and Gα14 reveals diversification of taste receptor cells in zebrafish.The Journal of comparative neurology · 2011Article
- Cladistic analysis of olfactory and vomeronasal systems.Frontiers in neuroanatomy · 2011Article
- The sea lamprey Petromyzon marinus genome reveals the early origin of several chemosensory receptor families in the vertebrate lineage.BMC evolutionary biology · 2009Article
- Origin of the genetic components of the vomeronasal system in the common ancestor of all extant vertebrates.Molecular biology and evolution · 2009Article
- Distinct evolutionary patterns between chemoreceptors of 2 vertebrate olfactory systems and the differential tuning hypothesis.Molecular biology and evolution · 2008Article
- Identification of a uniquely expanded V1R (ORA) gene family in the Japanese grenadier anchovy (Marine biologyArticle
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4 authors.
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No grant is acknowledged in the PubMed record.
Abstract
The survival of vertebrate species is dependent on the ability of individuals to adequately interact with each other, a function often mediated by the olfactory system. Diverse olfactory receptor repertoires are used by this system to recognize chemicals. Among these receptors, the V1rs, encoded by a very large gene family in most mammals, are able to detect pheromones. Teleosts, which also express V1r receptors, possess a very limited V1r repertoire. Here, taking advantage of the possibility to unequivocally identify V1r orthologs in teleosts, we analyzed the olfactory expression and evolutionary constraints of a pair of clustered fish V1r receptor genes, V1r1 and V1r2. Orthologs of the two genes were found in zebrafish, medaka, and threespine stickleback, but a single representative was observed in tetraodontidae species. Analysis of V1r1 and V1r2 sequences from 12 different euteleost species indicate different evolutionary rates between the two paralogous genes, leading to a highly conserved V1r2 gene and a V1r1 gene under more relaxed selective constraint. Moreover, positively-selected sites were detected in specific branches of the V1r1 clade. Our results suggest a conserved agonist specificity of the V1R2 receptor between euteleost species, its loss in the tetraodontidae lineage, and the acquisition of different chemosensory characteristics for the V1R1 receptor.
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