ArticleProceedings. Biological sciences2007
Virus infection causes specific learning deficits in honeybee foragers.
Article in Proceedings. Biological sciences, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 84 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
84 citing papers in PubMed, 1 synthesis or guideline pooled it, 175 citations in OpenAlex.
- Meta-analysis of honey bee neurogenomic response links Deformed wing virus type A to precocious behavioral maturation.Scientific reports · 2020Pooled it
- Never underestimate honeybees: Their exceptionally diverse adaptive strategies.Journal of advanced research · 2026Review
- Differential expression of neuronal function genes follows a tissue-specific temporal dynamic during Deformed Wing Virus infection in honeybees.Scientific reports · 2026Article
- Co-inoculation with deformed wing virus and sacbrood virus affects viral and immune dynamics and synergistically increases honey bee mortality.PLoS pathogens · 2026Article
- Deformed wing virus affects foraging success and foraging specialization of honeybee workers.Scientific reports · 2025Article
- Neurotranscriptomic profiling of deformed wing virus-infected honey bee foragers (Apis mellifera) with different cognitive abilities.Biology open · 2025Article
- The intensity of the transcriptional response varies across infection with distinct viral strains in an insect host.BMC genomics · 2025Article
- Genotype B of deformed wing virus and related recombinant viruses become dominant in European honey bee colonies.Scientific reports · 2025Article
- Binary Mixture of Neonicotinoid-Pyrethroid Insecticide: Impact on Survival, Cognitive Learning, and Memory inBiology · 2025Article
- Learning performance and GABAergic pathway link to deformed wing virus in the mushroom bodies of naturally infected honey bees.The Journal of experimental biology · 2024Article
- Article
- Nursing Honeybee Behavior and Sensorial-Related Genes Are Altered by Deformed Wing Virus Variant A.Insects · 2024Article
- Article
- Effects of Deformed Wing Virus-Targeting dsRNA on Viral Loads in Bees Parasitised and Non-Parasitised byViruses · 2023Article
- No impact of hygienic behavior and viral coinfection on the development of European foulbrood in honey bee (Apis mellifera) colonies during blueberry pollination in Michigan.Journal of insect science (Online) · 2023Article
- Doomed drones? Using passage experiments and mathematical modelling to determine Deformed wing virus population dynamics in male honeybees.Proceedings. Biological sciences · 2023Article
- Article
- Dietary Supplement of Grape Wastes Enhances Honeybee Immune System and Reduces Deformed Wing Virus (DWV) Load.Antioxidants (Basel, Switzerland) · 2022Article
- Virus Prevalence in Egg Samples Collected from Naturally Selected and Traditionally Managed Honey Bee Colonies across Europe.Viruses · 2022Article
- Chronic Cadmium Exposure Induces Impaired Olfactory Learning and Altered Brain Gene Expression in Honey Bees (Insects · 2022Article
24 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In both mammals and invertebrates, virus infections can impair a broad spectrum of physiological functions including learning and memory formation. In contrast to the knowledge on the conserved mechanisms underlying learning, the effects of virus infection on different aspects of learning are barely known. We use the honeybee (Apis mellifera), a well-established model system for studying learning, to investigate the impact of deformed wing virus (DWV) on learning. Injection of DWV into the haemolymph of forager leads to a RT-PCR detectable DWV signal after 3 days. The detailed behavioural analysis of DWV-infected honeybees shows an increased responsiveness to water and low sucrose concentrations, an impaired associative learning and memory formation, but intact non-associative learning like sensitization and habituation. This contradicts all present studies in non-infected bees, where increased sucrose responsiveness is linked to improved associative learning and to changes in non-associative learning. Thus, DWV seems to interfere with molecular mechanism of learning by yet unknown processes that may include viral effects on the immune system and on gene expression.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.