ReviewThe Journal of cell biology2007
Sending proteins to dense core secretory granules: still a lot to sort out.
Review in The Journal of cell biology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
59 citing papers in PubMed.
- Protein condensates in the the secretory pathway: Unraveling biophysical interactions and function.Biophysical journal · 2024Review
- Condensation of the β-cell secretory granule luminal cargoes pro/insulin and ICA512 RESP18 homology domain.Protein science : a publication of the Protein Society · 2023Article
- Cell-specific secretory granule sorting mechanisms: the role of MAGEL2 and retromer in hypothalamic regulated secretion.Frontiers in cell and developmental biology · 2023Review
- Liquid-liquid phase separation facilitates the biogenesis of secretory storage granules.The Journal of cell biology · 2022Article
- Small disulfide loops in peptide hormones mediate self-aggregation and secretory granule sorting.Life science alliance · 2022Article
- Nutrient Regulation of Pancreatic Islet β-Cell Secretory Capacity and Insulin Production.Biomolecules · 2022Review
- Efficient gene transfers into neocortical neurons connected by NMDA NR1-containing synapses.Journal of neuroscience methods · 2019Article
- Separate Gene Transfers into Pre- and Postsynaptic Neocortical Neurons Connected by mGluR5-Containing Synapses.Journal of molecular neuroscience : MN · 2019Article
- Chromogranin B regulates early-stage insulin granule trafficking from the Golgi in pancreatic islet β-cells.Journal of cell science · 2019Article
- ICA512 RESP18 homology domain is a protein-condensing factor and insulin fibrillation inhibitor.The Journal of biological chemistry · 2019Article
- Loss of Fam20c causes defects in the acinar and duct structure of salivary glands in mice.International journal of molecular medicine · 2019Article
- Delivery of different genes into pre- and post-synaptic neocortical interneurons connected by GABAergic synapses.PloS one · 2019Article
- POMC: The Physiological Power of Hormone Processing.Physiological reviews · 2018Review
- Paneth Cells during Viral Infection and Pathogenesis.Viruses · 2018Review
- Dense-core vesicle biogenesis and exocytosis in neurons lacking chromogranins A and B.Journal of neurochemistry · 2018Article
- Role of clathrin in dense core vesicle biogenesis.Molecular biology of the cell · 2017Article
- The Prohormone VGF Regulates β Cell Function via Insulin Secretory Granule Biogenesis.Cell reports · 2017Article
- Differential Maturation of the Two Regulated Secretory Pathways in Human iPSC-Derived Neurons.Stem cell reports · 2017Article
- Amyloid-like aggregation of provasopressin in diabetes insipidus and secretory granule sorting.BMC biology · 2017Article
- The EARP Complex and Its Interactor EIPR-1 Are Required for Cargo Sorting to Dense-Core Vesicles.PLoS genetics · 2016Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The intracellular sorting of peptide hormone precursors to the dense core secretory granules (DCSGs) is essential for their bioactivation. Despite the fundamental importance of this cellular process, the nature of the sorting signals for entry of proteins into DCSGs remains a source of vigorous debate. This review highlights recent discoveries that are consistent with a model in which several protein domains, acting in a cell-specific fashion and at different steps in the sorting process, act in concert to regulate the entry of proteins into DCSGs.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.