SynthesisAnnals of surgery2007
Prophylactic antibiotics for mesh inguinal hernioplasty: a meta-analysis.
Synthesis in Annals of surgery, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 6 syntheses or guidelines pooled it, 99 citations in OpenAlex.
- Antibiotic prophylaxis for prevention of postoperative wound infection in adults undergoing open elective inguinal or femoral hernia repair.The Cochrane database of systematic reviews · 2020Pooled it
- Network meta-analysis of antibiotic prophylaxis for prevention of surgical-site infection after groin hernia surgery.The British journal of surgery · 2017Pooled it
- Antibiotic prophylaxis for open mesh repair of groin hernia: systematic review and meta-analysis.Hernia : the journal of hernias and abdominal wall surgery · 2016Pooled it
- Mesh size in Lichtenstein repair: a systematic review and meta-analysis to determine the importance of mesh size.Hernia : the journal of hernias and abdominal wall surgery · 2013Pooled it
- Risk factors for mesh-related infections after hernia repair surgery: a meta-analysis of cohort studies.World journal of surgery · 2011Pooled it
- European Hernia Society guidelines on the treatment of inguinal hernia in adult patients.Hernia : the journal of hernias and abdominal wall surgery · 2009Guideline
- Prospective randomized evaluation of prophylactic antibiotic usage in patients undergoing tension free inguinal hernioplasty.Hernia : the journal of hernias and abdominal wall surgery · 2011Trial
- BODIPY-Functionalized Natural Polymer Coatings for Multimodal Therapy of Drug-Resistant Bacterial Infection.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023Article
- USA Department of Defense audit of surgical antibiotic prophylaxis prescribing patterns in inguinal hernia repair.Hernia : the journal of hernias and abdominal wall surgery · 2021Article
- Article
- Predictive factors for the development of surgical site infection in adults undergoing initial open inguinal hernia repair.Hernia : the journal of hernias and abdominal wall surgery · 2020Article
- Comparison of guideline recommendations for antimicrobial prophylaxis in urologic procedures: variability, lack of consensus, and contradictions.International urology and nephrology · 2018Review
- Medical pre-operative considerations for patients undergoing penile implantation.Translational andrology and urology · 2017Review
- SAGES guidelines for laparoscopic ventral hernia repair.Surgical endoscopy · 2016Article
- Do we need antibiotic prophylaxis in endoscopic inguinal hernia repair? Results of the Herniamed Registry.Surgical endoscopy · 2015Article
- Article
- Short- and long-term outcomes of incarcerated inguinal hernias repaired by Lichtenstein technique.Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques · 2014Article
- [Perioperative antibiotic prophylaxis].Der Anaesthesist · 2014Review
- Polypropylene mesh repair of incarcerated and strangulated hernias: a prospective clinical study.Surgery today · 2013Article
- [Hernia surgery in urology: part 1: inguinal, femoral and umbilical hernias - fundamentals of clinical diagnostics and treatment].Der Urologe. Ausg. A · 2013Review
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo assess the effectiveness of antibiotic prophylaxis in mesh hernioplasty.
backgroundAntibiotic prophylaxis use in mesh inguinal hernioplasty is controversial. Available evidence is nonconclusive because of the low number of clinical trials assessing its effectiveness. Some trials have a small sample size that could overestimate or underestimate the real effectiveness of this intervention. Meta-analysis is a good method to improve these methodological flaws.
methodsMeta-analysis intended to measure the benefits of antibiotic prophylaxis on surgical site infection rate in adult patients scheduled for mesh inguinal hernioplasty. Six randomized clinical trials were found. Quality was assessed using Cochrane Collaboration criteria.
resultsA total of 2507 patients were analyzed. Surgical site infection frequency was 1.38% in the antibiotic group versus 2.89% in the control group (odds ratio = 0.48; 95% confidence interval, 0.27-0.85). There was no statistical heterogeneity. Sensitivity analysis by quality did not show differences in overall results.
conclusionAntibiotic prophylaxis use in patients submitted to mesh inguinal hernioplasty decreased the rate of surgical site infection by almost 50%.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.