ArticleGenetics2007
The genetic architecture of shoot branching in Arabidopsis thaliana: a comparative assessment of candidate gene associations vs. quantitative trait locus mapping.
Article in Genetics, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
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Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it, 64 citations in OpenAlex.
- Genetic architecture of growth traits revealed by global epistatic interactions.Genome biology and evolution · 2011Pooled it
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- Genetic Mapping of Genotype-by-Ploidy Effects inGenes · 2023Article
- Identification of two tandem genes associated with primary rosette branching in flowering Chinese cabbage.Frontiers in plant science · 2022Article
- Network trade-offs and homeostasis in Arabidopsis shoot architectures.PLoS computational biology · 2019Article
- Identification of transcription factor genes involved in anthocyanin biosynthesis in carrot (Daucus carota L.) using RNA-Seq.BMC genomics · 2018Article
- Increasing branch and seed yield through heterologous expression of the novel rice S-acyl transferase geneBreeding science · 2018Article
- Genome-wide association mapping of quantitative traits in a breeding population of sugarcane.BMC plant biology · 2016Article
- Strigolactone pathway genes and plant architecture: association analysis and QTL detection for horticultural traits in chrysanthemum.Molecular genetics and genomics : MGG · 2016Article
- The extent and genetic basis of phenotypic divergence in life history traits in Mimulus guttatus.Molecular ecology · 2015Article
- Article
- The advantages and limitations of trait analysis with GWAS: a review.Plant methods · 2013Review
- Going with the wind--adaptive dynamics of plant secondary meristems.Mechanisms of development · 2013Article
- Epistatic natural allelic variation reveals a function of AGAMOUS-LIKE6 in axillary bud formation in Arabidopsis.The Plant cell · 2012Article
- Combined linkage and association mapping reveals CYCD5;1 as a quantitative trait gene for endoreduplication in Arabidopsis.Proceedings of the National Academy of Sciences of the United States of America · 2012Article
- Deciphering the genetics of flowering time by an association study on candidate genes in bread wheat (Triticum aestivum L.).TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2011Article
- Towards identifying genes underlying ecologically relevant traits in Arabidopsis thaliana.Nature reviews. Genetics · 2010Review
- Genetic and environmental control of the Verticillium syndrome in Arabidopsis thaliana.BMC plant biology · 2010Article
- Statistical epistasis between candidate gene alleles for complex tuber traits in an association mapping population of tetraploid potato.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2010Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Association mapping focused on 36 genes involved in branch development was used to identify candidate genes for variation in shoot branching in Arabidopsis thaliana. The associations between four branching traits and moderate-frequency haplogroups at the studied genes were tested in a panel of 96 accessions from a restricted geographic range in Central Europe. Using a mixed-model association-mapping method, we identified three loci--MORE AXILLARY GROWTH 2 (MAX2), MORE AXILLARY GROWTH 3 (MAX3), and SUPERSHOOT 1 (SPS1)--that were significantly associated with branching variation. On the basis of a more extensive examination of the MAX2 and MAX3 genomic regions, we find that linkage disequilibrium in these regions decays within approximately 10 kb and trait associations localize to the candidate genes in these regions. When the significant associations are compared to relevant quantitative trait loci (QTL) from previous Ler x Col and Cvi x Ler recombinant inbred line (RIL) mapping studies, no additive QTL overlapping these candidate genes are observed, although epistatic QTL for branching, including one that spans the SPS1, are found. These results suggest that epistasis is prevalent in determining branching variation in A. thaliana and may need to be considered in linkage disequilibrium mapping studies of genetically diverse accessions.
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