ArticleGenetics2007
Gametogenesis in the Chlamydomonas reinhardtii minus mating type is controlled by two genes, MID and MTD1.
Article in Genetics, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
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Who cites it
42 citing papers in PubMed, 91 citations in OpenAlex.
- The transcription factor PpRKD evokes female developmental fate in the sexual reproductive organs of Physcomitrium patens.The New phytologist · 2025Article
- Genome-Wide Survey of theInternational journal of molecular sciences · 2023Article
- Reorganization of the ancestral sex-determining regions during the evolution of trioecy in Pleodorina starrii.Communications biology · 2023Article
- From Feasting to Fasting: The Arginine Pathway as a Metabolic Switch in Nitrogen-DeprivedCells · 2023Review
- Genome-wide identification and characterization analysis of RWP-RK family genes reveal their role in flowering time of Chrysanthemum lavandulifolium.BMC plant biology · 2023Article
- Identification and Molecular Characterization of RWP-RK Transcription Factors in Soybean.Genes · 2023Article
- Transcriptional dynamics of gametogenesis in the green seaweed Ulva mutabilis identifies an RWP-RK transcription factor linked to reproduction.BMC plant biology · 2022Article
- HAP2-Mediated Gamete Fusion: Lessons From the World of Unicellular Eukaryotes.Frontiers in cell and developmental biology · 2021Review
- Conserved Subgroups of the Plant-Specific RWP-RK Transcription Factor Family Are Present in Oomycete Pathogens.Frontiers in microbiology · 2020Article
- A Series of Fortunate Events: Introducing Chlamydomonas as a Reference Organism.The Plant cell · 2019Review
- RPGRIP1L helps to establish the ciliary gate for entry of proteins.Journal of cell science · 2018Article
- UV Chromosomes and Haploid Sexual Systems.Trends in plant science · 2018Review
- Evolutionary divergence of the sex-determining geneDevelopment (Cambridge, England) · 2018Article
- Anisogamy evolved with a reduced sex-determining region in volvocine green algae.Communications biology · 2018Article
- Co-expression and Transcriptome Analysis ofFrontiers in plant science · 2018Article
- Genome-wide identification and characterization of gene family for RWP-RK transcription factors in wheat (Triticum aestivum L.).PloS one · 2018Article
- Genomic structure and evolution of the mating type locus in the green seaweed Ulva partita.Scientific reports · 2017Article
- Gene Regulatory Networks for the Haploid-to-Diploid Transition ofPlant physiology · 2017Article
- Sexual reproduction and sex determination in green algae.Journal of plant research · 2017Review
- The Transcription Factor NIN-LIKE PROTEIN7 Controls Border-Like Cell Release.Plant physiology · 2016Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In the unicellular algae Chlamydomonas reinhardtii, the plus and minus mating types are controlled by a complex locus, MT, where the dominant MID gene in the MT(-) locus has been shown to be necessary for expression of minus-specific gamete-specific genes in response to nitrogen depletion. We report studies on MID expression patterns during gametogenesis and on a second gene unique to the MT(-) locus, MTD1. Vegetative cells express basal levels of MID. An early activation of MID transcription after nitrogen removal, and its sequence similarity to plant RWP-RK proteins involved in nitrogen-responsive processes, suggest that Mid conformation/activity may be nitrogen sensitive. A second stage of MID upregulation correlates with the acquisition of mating ability in minus gametes. Knockdown of MTD1 by RNAi in minus strains results in a failure to differentiate into gametes of either mating type after nitrogen deprivation. We propose that intermediate Mid levels are sufficient to activate MTD1 transcription and to repress plus gamete-specific genes and that MTD1 expression in turn allows the threshold-level MID expression needed to turn on minus gamete-specific genes. We further propose that an MTD1-equivalent system, utilizing at least one gene product encoded in the MT(+) locus, is operant during plus gametogenesis.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.