Evidence map›Paper›PMID 17434660›Full record

ArticleUltrasound in medicine & biology2007

Quantification and MRI validation of regional contractile dysfunction in mice post myocardial infarction using high resolution ultrasound.

Yinbo Li, Christopher D Garson, Yaqin Xu, Ronald J Beyers, Frederick H Epstein, Brent A French, John A Hossack

Abstract read
In one paragraph

Article in Ultrasound in medicine & biology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guidelines for measuring cardiac physiology in mice.American journal of physiology. Heart and circulatory physiology · 2018
    Guideline
  2. Article
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  4. LncGBP9 knockdown alleviates myocardial inflammation and apoptosis in mice with acute viral myocarditis via suppressing NF-κB signaling pathway.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2022
    Article
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  7. Interleukin-38 alleviates cardiac remodelling after myocardial infarction.Journal of cellular and molecular medicine · 2020
    Article
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  9. Article
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  13. Reduced Myocardial Reserve in Young X-Linked Muscular Dystrophy Mice Diagnosed by Two-Dimensional Strain Analysis Combined with Stress Echocardiography.Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography · 2017
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yinbo LiDepartment of Biomedical Engineering, University of Virginia, Charlottesville, VA 22908-0759, USA.
Christopher D Garson
Yaqin Xu
Ronald J Beyers
Frederick H Epstein
Brent A French
John A Hossack

Funding

QUANTITATIVE 3D ULTRASOUND IMAGING OF THE MURINE HEARTR01EB001826 · NIBIB · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI HOSSACK, JOHN A · 2003 to 2012
$2.4M
GENE THERAPY FOR MYOCARDIAL STUNNING AND INFARCTIONR01HL058582 · NHLBI · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI FRENCH, BRENT A · 1997 to 2006
$872k
ULTRASOUND BIOMICROSCOPY OF SMALL ANIMAL ANATOMY AND PHYSIOLOGY WITH THE vevo 770S10RR022582 · NCRR · UNIVERSITY OF VIRGINIA · PI HOSSACK, JOHN A · 2006 to 2006
$234k
NCRR NIH HHS RR022582NCRR NIH HHS S10 RR022582NHLBI NIH HHS HL058582NHLBI NIH HHS R01 HL058582NIBIB NIH HHS EB001826NIBIB NIH HHS R01 EB001826
6 · The paper itself

Abstract

A versatile, computationally efficient two-dimensional (2D) speckle-tracking method based on high resolution ultrasound imaging is proposed to quantify regional myocardial dysfunction in mice. Ultrasound scans were performed on the hearts of normal and post myocardial infarction (MI) mice with a Vevo770 scanner (VisualSonics, Toronto, Canada) operating at 30 MHz frequency. Regional myocardial motion was tracked using a 2D minimum sum of absolute differences (MSAD) block-matching algorithm. Motion analyses calculated from ultrasound images were compared with gold-standard analyses performed using small animal magnetic resonance imaging (MRI). The radial and circumferential components of strain were compared between ultrasound and MRI short axis views and promising correlations were obtained (r = 0.90 and r = 0.85 for radial and circumferential strain, respectively). Therefore, ultrasound imaging, followed by 2D image tracking, provides an effective, low cost, mobile method to quantify murine cardiac function accurately and reliably.

Indexed as

AlgorithmsAnimalsEchocardiographyHeartImage Processing, Computer-AssistedMagnetic Resonance AngiographyMaleMiceMice, Inbred C57BLMyocardial ContractionMyocardial InfarctionRadiographyStress, MechanicalTime Factors

Identifiers

PMID17434660
PMCPMC2136434

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.