ArticleFertility and sterility2007
Prevalence of sexually transmissible pathogens in semen from asymptomatic male infertility patients with and without leukocytospermia.
Article in Fertility and sterility, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 82 papers, 7 of them syntheses that pooled it.
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Who cites it
82 citing papers in PubMed, 7 syntheses or guidelines pooled it.
- Evaluation of the Presence of Bacterial and Viral Agents in the Semen of Infertile Men: A Systematic and Meta-Analysis Review Study.Frontiers in medicine · 2022Pooled it
- Human papillomavirus in semen and the risk for male infertility: a systematic review and meta-analysis.BMC infectious diseases · 2017Pooled it
- Urogenital Infection as a Risk Factor for Male Infertility.Deutsches Arzteblatt international · 2017Pooled it
- Chlamydia (uncomplicated, genital).BMJ clinical evidence · 2015Pooled it
- Pooled it
- Impact of Chlamydia trachomatis in the reproductive setting: British Fertility Society Guidelines for practice.Human fertility (Cambridge, England) · 2010Guideline
- The risk of human papillomavirus infection for male fertility abnormality: a meta-analysis.Asian journal of andrologyPooled it
- Rethinking cytomegalovirus screening in gamete donation: a critical appraisal of practices and risks.Journal of assisted reproduction and genetics · 2026Article
- Chronic scrotal content pain and viral orchiepididymitis: an overlooked hypothesis linking infection and Wallerian degeneration.Basic and clinical andrology · 2026Review
- A viral glycoprotein targets IgGEMBO molecular medicine · 2026Article
- Protective role of gout against colorectal cancer: a Mendelian randomization study.Discover oncology · 2025Article
- Semen Microbiome, Male Infertility, and Reproductive Health.International journal of molecular sciences · 2025Review
- The possible pathogenic mechanisms of microorganisms in infertility: a narrative review.Archives of microbiology · 2025Review
- Retrospective analysis of the impact of human papillomavirus infection in the male genital tract on sperm: from a single center.Frontiers in cellular and infection microbiology · 2025Article
- Correlation between viral infections in male semen and infertility: a literature review.Virology journal · 2024Review
- Update on known and emergent viruses affecting human male genital tract and fertility.Basic and clinical andrology · 2024Review
- Unraveling the Intricacies of the Seminal Microbiome and Its Impact on Human Fertility.Biology · 2024Review
- Effect of leukocytes on semen quality in men from primary and secondary infertile couples: A cross-sectional study.Health science reports · 2023Article
- Viruses, bacteria and parasites: infection of the male genital tract and fertility.Basic and clinical andrology · 2023Review
- The Impact of Herpes Simplex Virus on Semen Parameters in Men with Idiopathic Infertility: A Systematic Review.International journal of fertility & sterility · 2023Article
22 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
objectiveTo determine the prevalence of pathogens that cause sexually transmitted infections (STIs) in semen from asymptomatic male infertility patients with and without leukocytospermia (LCS), and associations between STIs, inflammatory markers, and other semen variables.
designRetrospective, controlled study.
settingAcademic Medical Center. PATIENT(S): Two hundred and forty-one male infertility patients undergoing routine semen analysis: 132 with LCS, and 109 without LCS. INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): The DNA from STI pathogens (human papillomavirus [HPV], cytomegalovirus [CMV], herpes simplex virus [HSV], human herpesvirus type 6 [HHV-6], Epstein-Barr virus [EBV], hepatitis B virus [HBV], and Chlamydia trachomatis [CT]), routine semen parameters, and markers of accessory gland and epididymal function and inflammation. RESULT(S): The DNA from STI pathogens was detected in 45/241 (18.7%) of the samples (CMV, 8.7%; HPV, 4.5%; HHV-6, 3.7%; HSV, 3.7%; CT, 2.5%; EBV, 0.4%; and HBV, 0%), with no difference in prevalence between the LCS and non-LCS groups. The DNA of STI pathogens in semen was associated with a decrease in sperm concentration, motile sperm concentration, total sperm count, and neutral alpha-glucosidase concentration, whereas LCS was associated with a decrease in total sperm count, percent normal forms, and fructose concentration. CONCLUSION(S): The DNA of STI pathogens was detected in semen from a high percentage of asymptomatic male infertility patients, and was associated with poor semen quality. Efforts to diagnose and treat subclinical genital-tract infections should be intensified.
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