Evidence map›Paper›PMID 17431498›Full record

ReviewEnvironmental health perspectives2007

Adult lead exposure: time for change.

Brian S Schwartz, Howard Hu

Abstract readReview
In one paragraph

Review in Environmental health perspectives, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Combined Effect of Lead Exposure and Allostatic Load on Cardiovascular Disease Mortality-A Preliminary Study.International journal of environmental research and public health · 2021
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. More evidence of unpublished industry studies of lead smelter/refinery workers.International journal of occupational and environmental health · 2015
    Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Longitudinal changes in bone lead levels: the VA Normative Aging Study.Journal of occupational and environmental medicine · 2011
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Brian S SchwartzDepartment of Environmental Health Sciences and Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205, USA. bschwart@jhsph.edu
Howard Hu

Funding

Translational Research Support CoreP30ES000002 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI SUSAN A KORRICK · 1985 to 2026
$44.6M
VANADIUM AND HUMAN HEALTHP42ES005947 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI KELSEY, KARL TIMOTHY · 1992 to 2006
$19.6M
EXPLAINING DISPARITIES IN COGNITIVE FUNCTION IN SENIORSR01AG019604 · NIA · JOHNS HOPKINS UNIVERSITY · PI SCHWARTZ, BRIAN SETH · 2000 to 2011
$5.1M
AGE, LEAD EXPOSURE, AND NEUROBEHAVIORAL DECLINER01AG010785 · NIA · JOHNS HOPKINS UNIVERSITY · PI SCHWARTZ, BRIAN SETH · 1993 to 2007
$4.4M
LEAD-GENE INTERACTIONS AND CONGNITIONR01ES005257 · NIEHS · BRIGHAM AND WOMEN'S HOSPITAL · PI WEISSKOPF, MARC G · 1991 to 2007
$4.2M
Mechanisms for Adverse Renal Effects from Lead ExposureR01ES007198 · NIEHS · JOHNS HOPKINS UNIVERSITY · PI WEAVER, VIRGINIA M · 1997 to 2009
$3.1M
GENE-METAL INTERACTIONS AND PARKINSON'S DISEASER01ES010798 · NIEHS · BRIGHAM AND WOMEN'S HOSPITAL · PI HU, HOWARD · 2002 to 2006
$3.0M
NIA NIH HHS R01 AG010785NIA NIH HHS R01 AG019604NIA NIH HHS R01-AG10785NIA NIH HHS R01-AG19604NIEHS NIH HHS P30 ES000002NIEHS NIH HHS P30-ES00002NIEHS NIH HHS P42 ES005947NIEHS NIH HHS P42-ES05947NIEHS NIH HHS R01 ES005257NIEHS NIH HHS R01 ES007198NIEHS NIH HHS R01 ES010798NIEHS NIH HHS R01-ES05257NIEHS NIH HHS R01-ES07198NIEHS NIH HHS R01-ES10798
6 · The paper itself

Abstract

We have assembled this mini-monograph on adult lead exposure to provide guidance to clinicians and public health professionals, to summarize recent thinking on lead biomarkers and their relevance to epidemiologic research, and to review two key lead-related outcomes, namely, cardiovascular and cognitive. The lead standards of the U.S. Occupational Safety and Health Administration are woefully out of date given the growing evidence of the health effects of lead at levels of exposure previously thought to be safe, particularly newly recognized persistent or progressive effects of cumulative dose. The growing body of scientific evidence suggests that occupational standards should limit recent dose to prevent the acute effects of lead and separately limit cumulative dose to prevent the chronic effects of lead. We hope this mini-monograph will motivate renewed discussion of ways to protect lead-exposed adults in the United States and around the world.

Indexed as

AdultEnvironmental PollutantsHumansLeadOccupational ExposureUnited StatesUnited States Occupational Safety and Health AdministrationEnvironmental PollutantsLead

Identifiers

PMID17431498
PMCPMC1849904

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.