ArticleRetrovirology2007
The silent defense: micro-RNA directed defense against HIV-1 replication.
Article in Retrovirology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed.
- Activation of TLR3/interferon signaling pathway by bluetongue virus results in HIV inhibition in macrophages.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2015Article
- Toll-like receptor 3 signaling inhibits simian immunodeficiency virus replication in macrophages from rhesus macaques.Antiviral research · 2014Article
- Cellular RNA helicases and HIV-1: insights from genome-wide, proteomic, and molecular studies.Virus research · 2013Review
- A critical function of toll-like receptor-3 in the induction of anti-human immunodeficiency virus activities in macrophages.Immunology · 2010Article
- RNA interference: a multifaceted innate antiviral defense.Retrovirology · 2008Review
- HIV-1 TAR element is processed by Dicer to yield a viral micro-RNA involved in chromatin remodeling of the viral LTR.BMC molecular biology · 2007Article
- Nuclear Factor 90(NF90) targeted to TAR RNA inhibits transcriptional activation of HIV-1.Retrovirology · 2007Article
- Chromatin, gene silencing and HIV latency.Genome biology · 2007Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
MicroRNAs play critical role in regulating gene expression. MicroRNA profile of particular cell type bears the signature of cell type specific gene expression. Given that viral pathogens replicate by evading host defenses, research is now focused on the miRNA-regulated genes that critically regulate HIV-1 propagation in human host cells.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.