ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2007
Muscarinic control of long-range GABAergic inhibition within the rhinal cortices.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
27 citing papers in PubMed, 45 citations in OpenAlex.
- Spike-based coupling between single neurons and populations across rat sensory cortices, perirhinal cortex, and hippocampus.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Difference in axon diameter and myelin thickness between excitatory and inhibitory callosally projecting axons in mice.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Corticofugal VIP Gabaergic Projection Neurons in the Mouse Auditory and Motor Cortex.Frontiers in neural circuits · 2021Article
- The medial prefrontal cortex - hippocampus circuit that integrates information of object, place and time to construct episodic memory in rodents: Behavioral, anatomical and neurochemical properties.Neuroscience and biobehavioral reviews · 2020Review
- Network Plasticity Involved in the Spread of Neural Activity Within the Rhinal Cortices as Revealed by Voltage-Sensitive Dye Imaging in Mouse Brain Slices.Frontiers in cellular neuroscience · 2019Article
- Parvalbumin interneuron mediated feedforward inhibition controls signal output in the deep layers of the perirhinal-entorhinal cortex.Hippocampus · 2018Article
- Attenuated Activity across Multiple Cell Types and Reduced Monosynaptic Connectivity in the Aged Perirhinal Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2017Article
- Evidence for MNeuroscience · 2017Article
- Distribution of type I corticotropin-releasing factor (CRF1) receptors on GABAergic neurons within the basolateral amygdala.Synapse (New York, N.Y.) · 2017Article
- Functional neuroanatomy of amygdalohippocampal interconnections and their role in learning and memory.Journal of neuroscience research · 2017Review
- Distinct Spatiotemporal Activation Patterns of the Perirhinal-Entorhinal Network in Response to Cortical and Amygdala Input.Frontiers in neural circuits · 2016Article
- Excitatory Postrhinal Projections to Principal Cells in the Medial Entorhinal Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2015Article
- Molecular Genetic Strategies in the Study of Corticohippocampal Circuits.Cold Spring Harbor perspectives in biology · 2015Review
- Extrinsic origins of the somatostatin and neuropeptide Y innervation of the rat basolateral amygdala.Neuroscience · 2015Article
- GABAergic somatostatin-immunoreactive neurons in the amygdala project to the entorhinal cortex.Neuroscience · 2015Article
- Integration of exteroceptive and interoceptive information within the hippocampus: a computational study.Frontiers in systems neuroscience · 2015Article
- Perirhinal cortex and temporal lobe epilepsy.Frontiers in cellular neuroscience · 2013Review
- Differential connectivity of short- vs. long-range extrinsic and intrinsic cortical inputs to perirhinal neurons.The Journal of comparative neurology · 2013Article
- Intrinsic connections in the anterior part of the bed nucleus of the stria terminalis.Journal of neurophysiology · 2013Article
- Specialized cortical subnetworks differentially connect frontal cortex to parahippocampal areas.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2012Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
The perirhinal cortex plays a critical role in memory formation, in part because it forms reciprocal connections with the neocortex and entorhinal cortex and is thus in a position to integrate and transfer higher-order information to and from the hippocampus. However, for reasons that remain unclear, perirhinal transfer of neocortical inputs to the entorhinal cortex occurs with a low probability. Using patch recordings in vitro and tract-tracing combined with GAD-67 immunohistochemistry, we show that the perirhinal cortex contains GABAergic neurons with long-range projections to superficial entorhinal cells. This finding challenges the traditional model of cortical inhibition in which all trans-areal inhibition is thought to be disynaptic because the axons of GABAergic interneurons are assumed to be confined within the area in which their somata are located. Moreover, consistent with recent studies indicating that the formation of perirhinal-dependent memories requires activation of muscarinic receptors, long-range IPSPs were presynaptically inhibited by M2 receptor activation. Overall, these results suggest that long-range feedforward inhibition regulates perirhinal transfer of neocortical inputs to the entorhinal cortex, but that cholinergic inputs can presynaptically adjust the impact of this control mechanism as a function of environmental contingencies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.