ReviewClinical microbiology reviews2007
Human protothecosis.
Review in Clinical microbiology reviews, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 115 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
115 citing papers in PubMed, 290 citations in OpenAlex.
- Experimental protothecosis in a murine model.PLoS neglected tropical diseases · 2026Article
- High-Quality Genome Assemblies of Two Prototheca wickerhamii Strains.Scientific data · 2026Article
- The virulence potential ofFrontiers in cellular and infection microbiology · 2026Article
- Cutaneous Protothecosis: Reported Human Cases in Vietnam and Diagnostic Challenges.Case reports in dermatological medicine · 2026Article
- Skin microbiome dysbiosis inhLife · 2025Article
- Green Nanoparticle Synthesis in the Application of Non-Bacterial Mastitis in Cattle.Molecules (Basel, Switzerland) · 2025Article
- Herbicide glyphosate efficiently inhibits growth of pathogenicMicrobiology spectrum · 2025Article
- Disseminated protothecosis in a dog coinfected with Hepatozoon canis and Ehrlichia canis.Veterinary research communications · 2025Article
- Pediatric Meningeal Diseases: What Radiologists Need to Know.Tomography (Ann Arbor, Mich.) · 2024Review
- Phenotypic and molecular characterization of Prototheca wickerhamii from a Brazilian case of human systemic protothecosis.PLoS neglected tropical diseases · 2024Article
- Successful Treatment of Refractory Cutaneous Protothecosis With MAT2203, an Oral Lipid Nanocrystal Formulation of Amphotericin B.Open forum infectious diseases · 2024Article
- Effects of essential oils on economically important characteristics of ruminant species: A comprehensive review.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2024Review
- Successful Treatment of Cutaneous Protothecosis Due toClinical, cosmetic and investigational dermatology · 2024Article
- Obstructive Hydrocephalus and Cardiomyopathy Secondary to Disseminated Protothecosis in a Boxer Dog.Case reports in veterinary medicine · 2024Article
- Simultaneous infection withMedical mycology case reports · 2023Article
- Identification ofVeterinary sciences · 2023Article
- The Development of a Multiplex PCR Assay for Fast and Cost-Effective Identification of the Five Most Significant PathogenicPathogens (Basel, Switzerland) · 2023Article
- Human protothecosis: A case report in northeastern Brazil.Medical mycology case reports · 2023Article
- Article
- Drug Susceptibility Profiling ofAntimicrobial agents and chemotherapy · 2023Article
55 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Human protothecosis is a rare infection caused by members of the genus Prototheca. Prototheca species are generally considered to be achlorophyllic algae and are ubiquitous in nature. The occurrence of protothecosis can be local or disseminated and acute or chronic, with the latter being more common. Diseases have been classified as (i) cutaneous lesions, (ii) olecranon bursitis, or (iii) disseminated or systemic manifestations. Infections can occur in both immunocompetent and immunosuppressed patients, although more severe and disseminated infections tend to occur in immunocompromised individuals. Prototheca wickerhamii and Prototheca zopfii have been associated with human disease. Usually, treatment involves medical and surgical approaches; treatment failure is not uncommon. Antifungals such as ketoconazole, itraconazole, fluconazole, and amphotericin B are the most commonly used drugs to date. Among them, amphotericin B displays the best activity against Prototheca spp. Diagnosis is largely made upon detection of characteristic structures observed on histopathologic examination of tissue.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.