ArticleBMC genomics2007
The use of global transcriptional analysis to reveal the biological and cellular events involved in distinct development phases of Trichophyton rubrum conidial germination.
Article in BMC genomics, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
34 citing papers in PubMed, 68 citations in OpenAlex.
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- Does sorghum phenolic extract have antifungal effect?Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2024Article
- Dermatophyte infection: from fungal pathogenicity to host immune responses.Frontiers in immunology · 2023Review
- Genome-wide identification and functional analysis of circRNAs in Trichophyton rubrum conidial and mycelial stages.BMC genomics · 2022Article
- Proteome-Wide Identification and Functional Analysis of Lysine Crotonylation inFrontiers in genetics · 2022Article
- Transcription in fungal conidia before dormancy produces phenotypically variable conidia that maximize survival in different environments.Nature microbiology · 2021Article
- Evaluation of an Explanted Porcine Skin Model to Investigate Infection with the Dermatophyte Trichophyton rubrum.Mycopathologia · 2020Article
- Proteome-Wide Identification of Lysine Propionylation in the Conidial and Mycelial Stages ofFrontiers in microbiology · 2019Article
- Integrated microRNA and mRNA analysis in the pathogenic filamentous fungus Trichophyton rubrum.BMC genomics · 2018Article
- Identification of differentially expressed genes involved in spore germination of Penicillium expansum by comparative transcriptome and proteome approaches.MicrobiologyOpen · 2018Article
- The first succinylome profile of Trichophyton rubrum reveals lysine succinylation on proteins involved in various key cellular processes.BMC genomics · 2017Article
- Transcription profile of Trichophyton rubrum conidia grown on keratin reveals the induction of an adhesin-like protein gene with a tandem repeat pattern.BMC genomics · 2016Article
- Use of Restriction Fragment Length Polymorphism to Rapidly Identify Dermatophyte Species Related to Dermatophytosis.Jundishapur journal of microbiology · 2015Article
- Evaluation of Antifungal Activity and Mode of Action of New Coumarin Derivative, 7-Hydroxy-6-nitro-2H-1-benzopyran-2-one, against Aspergillus spp.Evidence-based complementary and alternative medicine : eCAM · 2015Article
- Analysis of gene expression changes in Trichophyton rubrum after skin interaction.Journal of medical microbiology · 2014Article
- Identification and characterisation of non-coding small RNAs in the pathogenic filamentous fungus Trichophyton rubrum.BMC genomics · 2013Article
- Analysis of Phakopsora pachyrhizi transcript abundance in critical pathways at four time-points during infection of a susceptible soybean cultivar using deep sequencing.BMC genomics · 2013Article
Corrections and comments
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Authors and funding
26 authors at 6 institutions in 1 country.
Funding
Abstract
backgroundConidia are considered to be the primary cause of infections by Trichophyton rubrum.
resultsWe have developed a cDNA microarray containing 10250 ESTs to monitor the transcriptional strategy of conidial germination. A total of 1561 genes that had their expression levels specially altered in the process were obtained and hierarchically clustered with respect to their expression profiles. By functional analysis, we provided a global view of an important biological system related to conidial germination, including characterization of the pattern of gene expression at sequential developmental phases, and changes of gene expression profiles corresponding to morphological transitions. We matched the EST sequences to GO terms in the Saccharomyces Genome Database (SGD). A number of homologues of Saccharomyces cerevisiae genes related to signalling pathways and some important cellular processes were found to be involved in T. rubrum germination. These genes and signalling pathways may play roles in distinct steps, such as activating conidial germination, maintenance of isotropic growth, establishment of cell polarity and morphological transitions.
conclusionOur results may provide insights into molecular mechanisms of conidial germination at the cell level, and may enhance our understanding of regulation of gene expression related to the morphological construction of T. rubrum.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.