Evidence map›Paper›PMID 17428331›Full record

ArticleGenome biology2007

A major zebrafish polymorphism resource for genetic mapping.

Kevin M Bradley, J Bradford Elmore, Joan P Breyer, Brian L Yaspan, Jason R Jessen, Ela W Knapik, Jeffrey R Smith

Abstract read
In one paragraph

Article in Genome biology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Article
  3. Genome and Transcriptome Sequencing ofInternational journal of molecular sciences · 2020
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
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  12. Article
  13. Extensive genetic diversity and substructuring among zebrafish strains revealed through copy number variant analysis.Proceedings of the National Academy of Sciences of the United States of America · 2012
    Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kevin M BradleyDepartment of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232-0275, USA. Kevin.bradley@vanderbilt.edu
J Bradford Elmore
Joan P Breyer
Brian L Yaspan
Jason R Jessen
Ela W Knapik
Jeffrey R Smith

Funding

MULTIDISCIPLINARY BASIC RESEARCH TRAINING IN CANCERT32CA009592 · NCI · VANDERBILT UNIVERSITY · PI Justin M Balko, Julie A Rhoades (Sterling) · 1987 to 2026
$10.4M
Genetic Mapping Resource for ZebrafishR01DK065637 · NIDDK · VANDERBILT UNIVERSITY · PI SMITH, JEFFREY R. · 2003 to 2007
$1.7M
NCI NIH HHS T32 CA009592NIDDK NIH HHS R01 DK065637
6 · The paper itself

Abstract

We have identified 645,088 candidate polymorphisms in zebrafish and observe a single nucleotide polymorphism (SNP) validation rate of 71% to 86%, improving with polymorphism confidence score. Variant sites are non-random, with an excess of specific novel T- and A-rich motifs. We positioned half of the polymorphisms on zebrafish genetic and physical maps as a resource for positional cloning. We further demonstrate bulked segregant analysis using the anchored SNPs as a method for high-throughput genetic mapping in zebrafish.

Indexed as

Polymorphism, Single NucleotideAnimalsChromosome MappingCloning, MolecularGenetic LinkageGenetic MarkersZebrafishGenetic Markers

Identifiers

PMID17428331
PMCPMC1896001

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.