Evidence map›Paper›PMID 17420214›Full record

ArticleAntimicrobial agents and chemotherapy2007

Inhibitory activities of three classes of acyclic nucleoside phosphonates against murine polyomavirus and primate simian virus 40 strains.

Ilya Lebeau, Graciela Andrei, Marcela Krecmerová, Erik De Clercq, Antonin Holy, Robert Snoeck

Open access · greenAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Anti-BK virus activity of nucleoside analogs.Antimicrobial agents and chemotherapy · 2008
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Ilya LebeauRega Institute for Medical Research, K.U. Leuven, Minderbroedersstraat 10, Leuven, Belgium.
Graciela Andrei
Marcela Krecmerová
Erik De Clercq
Antonin Holy
Robert Snoeck
KU Leuven · BECzech Academy of Sciences, Institute of Organic Chemistry and Biochemistry · CZRega Institute for Medical Research · BE

Funding

Novel inhibitors of the replication of poxvirusesUC1AI062540 · NIAID · KATHOLIEKE UNIVERSITEIT LEUVEN · PI NEYTS, JOHAN H · 2004 to 2004
$1.6M
NIAID NIH HHS AI 062540-01NIAID NIH HHS UC1 AI062540
6 · The paper itself

Abstract

Murine polyomavirus and simian virus 40 were used to evaluate the potencies of the compounds of three classes of acyclic nucleoside phosphonates: (i) the original HPMP (3-hydroxy-2-phosphonomethoxypropyl) and PME (2-phosphonomethoxyethyl) derivatives, (ii) the 6-[2-(phosphonomethoxy)alkoxy]-2,4-diaminopyrimidine (DAPy) derivatives, and (iii) a new class of HPMP derivatives containing a 5-azacytosine moiety. The last class showed the highest activities and selectivities against both polyomaviruses.

Indexed as

AnimalsAntiviral AgentsCell LineCidofovirCytosineMiceMicrobial Sensitivity TestsNucleosidesOrganophosphonatesPolyomavirusPyrimidine NucleosidesPyrimidinesSimian virus 402,4-diaminopyrimidineAntiviral AgentsCidofovirCytosineNucleosidesOrganophosphonatesPyrimidine NucleosidesPyrimidines

Identifiers

PMID17420214
PMCPMC1891398
OpenAlexW2139759293

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.