Evidence map›Paper›PMID 17418055›Full record

ReviewCurrent gastroenterology reports2007

Predicting severity of acute pancreatitis.

Bettina M Rau

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current gastroenterology reports, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 42 citations in OpenAlex.

  1. Changes in cytokines and chemokines in an acute pancreatitis model.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2024
    Article
  2. Article
  3. Dynamic nature of organ failure in severe acute pancreatitis: the impact of persistent and deteriorating organ failure.HPB : the official journal of the International Hepato Pancreato Biliary Association · 2013
    Observational
  4. Predictors of adverse outcomes in acute pancreatitis: new horizons.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2013
    Review
  5. Serum amyloid a protein in clinical cancer diagnosis.Pathology oncology research : POR · 2012
    Article
  6. Article
  7. Article
  8. Early management of severe acute pancreatitis.Current gastroenterology reports · 2011
    Review
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Bettina M RauDepartment of General, Visceral, and Vascular Surgery, University of the Saarland, Kirrberger Strasse, Building 57, 66421 Homburg/Saar, Germany. bettina.rau@uniklinikum-saarland.de
Saarland University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Severity stratification is a critical issue in acute pancreatitis that strongly influences diagnostic and therapeutic decision making. According to the widely used Atlanta classification, "severe" disease comprises various local and systemic complications that are associated with an increased risk of mortality. However, results from recent clinical studies indicate that these complications vary in their effect on outcome, and many are not necessarily life threatening on their own. Therefore, "severe," as defined by Atlanta, must be distinguished from "prognostic," aiming at nonsurvival. In the first week after disease onset, pancreatitis-related organ failure is the preferred variable for predicting severity and prognosis because it outweighs morphologic complications. Contrast-enhanced CT and MRI allow for accurate stratification of local severity beyond the first week after symptom onset. Among the biochemical markers, C-reactive protein is still the parameter of choice to assess attack severity, although prognostic estimation is not possible. Other markers, including pancreatic protease activation peptides, interleukins-6 and -8, and polymorphonuclear elastase are useful early indicators of severity. Procalcitonin is one of the most promising single markers for assessment of major complications and prognosis throughout the disease course.

Indexed as

APACHEBlood Coagulation DisordersCalcitoninCalcitonin Gene-Related PeptideCytokinesHumansLeukocyte ElastaseMultiple Organ FailurePancreatitisPeptidesProtein PrecursorsSerum Amyloid A ProteinSeverity of Illness IndexCALCA protein, humanCalcitoninCalcitonin Gene-Related Peptidecarboxypeptidase B activation peptideCytokinesLeukocyte ElastasePeptidesProtein PrecursorsSerum Amyloid A Protein

Identifiers

PMID17418055
OpenAlexW1995229169

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.