ArticleNeurotoxicology and teratology
Pre-natal exposures to cocaine and alcohol and physical growth patterns to age 8 years.
Article in Neurotoxicology and teratology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 43 citations in OpenAlex.
- Fetal alcohol-related growth restriction from birth through young adulthood and moderating effects of maternal prepregnancy weight.Alcoholism, clinical and experimental research · 2013Trial
- Prenatal Alcohol Exposure and Mitochondrial Function in the Brain.Advances in experimental medicine and biology · 2026Review
- Gestational weight gain and dietary energy, iron, and choline intake predict severity of fetal alcohol growth restriction in a prospective birth cohort.The American journal of clinical nutrition · 2022Article
- Diagnosis of Fetal Alcohol Spectrum Disorders (FASDs): Guidelines of Interdisciplinary Group of Polish Professionals.International journal of environmental research and public health · 2021Article
- The causal web of foetal alcohol spectrum disorders: a review and causal diagram.European child & adolescent psychiatry · 2020Review
- Fetal Alcohol Growth Restriction and Cognitive Impairment.Pediatrics · 2016Article
- Prenatal cocaine effects on brain structure in early infancy.NeuroImage · 2014Article
- Epidemiology of substance use in reproductive-age women.Obstetrics and gynecology clinics of North America · 2014Review
- Externalizing behavior and substance use related problems at 15 years in prenatally cocaine exposed adolescents.Journal of adolescence · 2014Article
- Effects of heavy prenatal alcohol exposure and iron deficiency anemia on child growth and body composition through age 9 years.Alcoholism, clinical and experimental research · 2012Article
- The effects of prenatal methamphetamine exposure on childhood growth patterns from birth to 3 years of age.American journal of perinatology · 2012Article
- Prenatal cocaine exposure alters progenitor cell markers in the subventricular zone of the adult rat brain.International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience · 2012Article
- Risk for obesity in adolescence starts in early childhood.Journal of perinatology : official journal of the California Perinatal Association · 2011Article
- Prenatal cocaine exposure and BMI and blood pressure at 9 years of age.Journal of hypertension · 2010Article
- Review
- Can prenatal ultrasound detect the effects of in-utero alcohol exposure? A pilot study.Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology · 2009Article
- Early adolescent cocaine use as determined by hair analysis in a prenatal cocaine exposure cohort.Neurotoxicology and teratologyArticle
- Cognitive development and low-level lead exposure in poly-drug exposed children.Neurotoxicology and teratologyArticle
- Effects of prenatal cocaine exposure on adolescent development.Neurotoxicology and teratologyArticle
- Prenatal cocaine exposure alters emotional arousal regulation and its effects on working memory.Neurotoxicology and teratologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
Two hundred and two primarily African American/Caribbean children (classified by maternal report and infant meconium as 38 heavier, 74 lighter and 89 not cocaine-exposed) were measured repeatedly from birth to age 8 years to assess whether there is an independent effect of pre-natal cocaine exposure on physical growth patterns. Children with fetal alcohol syndrome identifiable at birth were excluded. At birth, cocaine and alcohol exposures were significantly and independently associated with lower weight, length and head circumference in cross-sectional multiple regression analyses. The relationship over time of pre-natal exposures to weight, height, and head circumference was then examined by multiple linear regression using mixed linear models including covariates: child's gestational age, gender, ethnicity, age at assessment, current caregiver, birth mother's use of alcohol, marijuana and tobacco during the pregnancy and pre-pregnancy weight (for child's weight) and height (for child's height and head circumference). The cocaine effects did not persist beyond infancy in piecewise linear mixed models, but a significant and independent negative effect of pre-natal alcohol exposure persisted for weight, height, and head circumference. Catch-up growth in cocaine-exposed infants occurred primarily by 6 months of age for all growth parameters, with some small fluctuations in growth rates in the preschool age range but no detectable differences between heavier versus unexposed nor lighter versus unexposed thereafter.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.