Evidence map›Paper›PMID 17409215›Full record

ArticleJournal of clinical microbiology2007

Addition of neuA, the gene encoding N-acylneuraminate cytidylyl transferase, increases the discriminatory ability of the consensus sequence-based scheme for typing Legionella pneumophila serogroup 1 strains.

Sandra Ratzow, Valeria Gaia, Jürgen Herbert Helbig, Norman K Fry, Paul Christian Lück

Abstract readEvaluation Study
In one paragraph

Article in Journal of clinical microbiology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 131 papers.

0numbers the graph read from it
0cells of the map it votes in
131citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

131 citing papers in PubMed.

  1. Fine-scale structural diversification among closely relatedApplied and environmental microbiology · 2026
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  2. Draft genome sequences of 20Microbiology resource announcements · 2026
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  3. 'Epidemiology ofMicrobial genomics · 2026
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  4. MixedInfectious disease reports · 2026
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  5. Genomic characterization ofPathogens and global health · 2026
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  6. Article
  7. Article
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  9. Comparison of whole genome sequencing typing tools for the typing of Belgian Legionella pneumophila outbreaks isolates.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025
    Article
  10. Article
  11. Detection ofJournal of water and health · 2024
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  12. Article
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  15. Case report: First report ofFrontiers in medicine · 2024
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  17. Review
  18. Long-read sequencing for reliably calling theFrontiers in cellular and infection microbiology · 2023
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  19. Whole-genome sequencing of the clinical isolate ofEuropean clinical respiratory journal · 2023
    Article
  20. Investigation of aMicroorganisms · 2022
    Article

71 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sandra RatzowInstitut für Medizinische Mikrobiologie und Hygiene, TU Dresden, Fiedlerstrasse 42, D-01307 Dresden, Germany.
Valeria Gaia
Jürgen Herbert Helbig
Norman K Fry
Paul Christian Lück

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The standard sequence-based method for the typing of Legionella pneumophila serogroup 1 strains was extended by using the gspA and neuA alleles. The use of neuA as a seventh allele for typing significantly increased the index of discrimination calculated for a panel of unrelated strains (from 0.932 to 0.963) and subdivided some known large common complexes (e.g., 1,4,3,1,1,1). This modification to the standard method is proposed as the method of choice in the epidemiological investigation of L. pneumophila infections.

Indexed as

Bacterial Typing TechniquesConsensus SequenceAllelesBacterial ProteinsHeat-Shock ProteinsHumansLegionella pneumophilaLegionnaires' DiseaseMolecular Sequence DataN-Acylneuraminate CytidylyltransferaseSequence Analysis, DNASerotypingBacterial Proteinsglobal stress protein A, bacteriaHeat-Shock ProteinsN-Acylneuraminate Cytidylyltransferase

Identifiers

PMID17409215
PMCPMC1933043

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.