Evidence map›Paper›PMID 17408905›Full record

ReviewInternational journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience2007

Demyelinating diseases and potential repair strategies.

C Radtke, M Spies, M Sasaki, P M Vogt, J D Kocsis

Open access · greenAbstract readReview
In one paragraph

Review in International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.6field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Myelin repair strategies: a cellular view.Current opinion in neurology · 2008
    Review
  12. Therapeutic benefits by human mesenchymal stem cells (hMSCs) and Ang-1 gene-modified hMSCs after cerebral ischemia.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2008
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

C RadtkeDepartment of Neurology, Yale University School of Medicine, New Haven, CT 06516, USA.
M Spies
M Sasaki
P M Vogt
J D Kocsis
VA Connecticut Healthcare System · USMedizinische Hochschule Hannover · DE

Funding

YALE EPILEPSY RESEARCH CENTERP50NS006208 · NINDS · YALE UNIVERSITY · PI RICHERSON, GEORGE B · 1985 to 2001
$2.2M
NINDS NIH HHS P50 NS006208
6 · The paper itself

Abstract

Demyelination is associated with a number of neurological disorders including multiple sclerosis (MS), spinal cord injury and nerve compression. MS lesions often show axon loss and therefore reparative therapeutic goals include remyelination and neuroprotection of vulnerable axons. Experimental cellular transplantation has proven successful in a number of demyelination and injury models to remyelinate and improve functional outcome. Here we discuss the remyelination and neuroprotective potential of several myelin-forming cells types and their behavior in different demyelination and injury models. Better understanding of these models and current cell-based strategies for remyelination and neuroprotection offer exciting opportunities to develop strategies for clinical studies.

Indexed as

AnimalsCell TransplantationDemyelinating DiseasesDisease Models, AnimalHumansMyelin SheathNerve Regeneration

Identifiers

PMID17408905
PMCPMC2692731
OpenAlexW2067414152

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.