ArticleNature protocols2006
Use of a commercially available reagent for the selective detection of homocysteine in plasma.
Article in Nature protocols, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed.
- Article
- Fluorescent Probes with Multiple Binding Sites for the Discrimination of Cys, Hcy, and GSH.Angewandte Chemie (International ed. in English) · 2017Review
- Fluorescein Tri-Aldehyde Promotes the Selective Detection of Homocysteine.Journal of fluorescence · 2016Article
- Differences in heterocycle basicity distinguish homocysteine from cysteine using aldehyde-bearing fluorophores.Chemical communications (Cambridge, England) · 2014Article
- A photochemical method for determining plasma homocysteine with limited sample processing.Chemical communications (Cambridge, England) · 2014Article
- Thiol reactive probes and chemosensors.Sensors (Basel, Switzerland) · 2012Review
- Homocystamides promote free-radical and oxidative damage to proteins.Proceedings of the National Academy of Sciences of the United States of America · 2010Article
- Gold nanoparticle sensor for homocysteine thiolactone-induced protein modification.Langmuir : the ACS journal of surfaces and colloids · 2008Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
A procedure for the detection of homocysteine (Hcy) in blood plasma is described. A commercially available chromogen is added to the plasma sample. The plasma solution turns from yellow to blue upon heating for 4 min when a detectable threshold level of Hcy is present. Chromatographic separations and immunogenic materials are not needed. The protocol takes approximately 30 min.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.