Evidence map›Paper›PMID 17401688›Full record

SynthesisDigestive diseases and sciences2007

The role of smoking in Crohn's disease as defined by clinical variables.

Suhal S Mahid, Kyle S Minor, Patrick L Stevens, Susan Galandiuk

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Digestive diseases and sciences, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Genetic and environmental factors influencing Crohn's disease.World journal of gastrointestinal surgery · 2025
    Article
  5. Article
  6. Review
  7. Comprehensive review and update of stricturing Crohn's disease.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2024
    Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Health Maintenance in Inflammatory Bowel Disease.Current gastroenterology reports · 2018
    Review
  13. Article
  14. Article
  15. Observational
  16. Influence of environmental factors in the development of inflammatory bowel diseases.World journal of gastrointestinal pharmacology and therapeutics · 2016
    Review
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Suhal S MahidDepartment of Surgery, University of Louisville School of Medicine, Louisville, Kentucky 40292, USA.
Kyle S Minor
Patrick L Stevens
Susan Galandiuk

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The development of Crohn's disease (CD) is related to an interaction of genetic and environmental factors, with tobacco smoking being one of the most commonly studied environmental factors. In 1998, the Vienna classification was created to define CD by using three accepted clinical variables: age at diagnosis, disease behavior, and disease location. In this qualitative systematic review, articles examining the relationship between smoking and CD, using variables outlined in the Vienna classification, were identified utilizing multiple health databases. Current smoking was found to be associated with late-onset CD (> or =40 years old) and current smokers were more likely to progress to stricturing or penetrating type CD than were nonsmoking patients. Conflicting evidence exists regarding the relationship between smoking with respect to CD disease location. The Vienna classification is an important tool in permitting comparisons and predicting clinical course among CD cases, especially when smoking status is taken into account.

Indexed as

Age of OnsetCrohn DiseaseGlobal HealthHumansRisk FactorsSmokingTobacco Smoke PollutionTobacco Smoke Pollution

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.