Evidence map›Paper›PMID 17400472›Full record

ReviewSeminars in immunology2007

Molecular mechanisms for adaptive tolerance and other T cell anergy models.

Seeyoung Choi, Ronald H Schwartz

Abstract readReview
In one paragraph

Review in Seminars in immunology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed.

  1. Article
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  16. Exhaustion-associated regulatory regions in CD8Proceedings of the National Academy of Sciences of the United States of America · 2017
    Article
  17. Review
  18. Review
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Seeyoung ChoiNational Institutes of Health, LCMI, NIAID, Bethesda, MD 20892-0420, USA.
Ronald H Schwartz

Funding

T CELL ACTIVATIONZ01AI000485 · NIAID · NIAID EXTRAMURAL ACTIVITIES · PI SCHWARTZ, RONALD · 1987 to 2008
$2.6M
Intramural NIH HHS Z01 AI000485
6 · The paper itself

Abstract

Since the original description of T cell anergy in CD4 clones from mice and humans, a number of different unresponsive states have been described, both in vivo and in vitro, that have been called anergic. While initial attempts were made to understand the similarities between the different models, it has now become clear from biochemical experiments that many of them have different molecular mechanisms underlying their unresponsiveness. In this review we will detail our own work on the in vivo model referred to as adaptive tolerance and then attempt to compare this biochemical state to the multitude of other states that have been described in the literature.

Indexed as

Adoptive TransferAnimalsClonal AnergyHumansImmune ToleranceMiceT-Lymphocytes

Identifiers

PMID17400472
PMCPMC2045643

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.