Evidence map›Paper›PMID 17394036›Full record

ArticleClinical rheumatology2007

Cardiac sarcoidosis responding to monotherapy with infliximab.

Imad Uthman, Zahi Touma, Maurice Khoury

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in Clinical rheumatology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 74 citations in OpenAlex.

  1. Review
  2. Controversies in the Treatment of Cardiac Sarcoidosis.Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG · 2022
    Article
  3. Review
  4. Article
  5. Article
  6. TNF-alpha inhibition for the treatment of cardiac sarcoidosis.Seminars in arthritis and rheumatism · 2020
    Article
  7. Observational
  8. Article
  9. Article
  10. Article
  11. A Diagnostic and Therapeutic Approach to Arrhythmias in Cardiac Sarcoidosis.Current treatment options in cardiovascular medicine · 2016
    Article
  12. Review
  13. Cardiac involvement in sarcoidosis: evolving concepts in diagnosis and treatment.Seminars in respiratory and critical care medicine · 2014
    Review
  14. Review
  15. Review
  16. Article
  17. Cardiac sarcoidosis: diagnosis and management.Current treatment options in cardiovascular medicine · 2012
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Imad UthmanDepartment of Internal Medicine, Faculty of Medicine, American University of Beirut Medical Center, P.O. Box 113-6044, Hamra Street, Beirut, 1103 2090, Lebanon. iuthman@aub.edu.lb
Zahi Touma
Maurice Khoury
American University of Beirut Medical Center · LB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiac involvement is a rare and potentially life-threatening complication of sarcoidosis. We report the case of a young previously healthy woman who presented with complete atrioventricular heart block. Further evaluation revealed non-caseating granulomas in the hilar and mediastinal regions. A pacemaker was inserted, and she was treated with four doses of infliximab after she refused treatment with steroids. Rapid resolution of the pulmonary lymph nodes was documented and repeated interrogations of the pacemaker 1 year after her last infliximab infusion documented that she was in sinus rhythm. Infliximab may be considered as an alternative first-line therapy in sarcoidosis with serious organ involvement.

Indexed as

AdultAntibodies, MonoclonalAntirheumatic AgentsCardiomyopathiesFemaleHeart BlockHumansInfliximabLymph NodesMyocardiumSarcoidosisTreatment OutcomeAntibodies, MonoclonalAntirheumatic AgentsInfliximab

Identifiers

PMID17394036
OpenAlexW1976662542

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.