ReviewLipids2007
Molecular genetics of plant sterol backbone synthesis.
Review in Lipids, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 69 citations in OpenAlex.
- Article
- Updated aspects of alpha-Solanine as a potential anticancer agent: Mechanistic insights and future directions.Food science & nutrition · 2024Review
- Article
- Natural variation and underlying genetic loci of γ-oryzanol in Asian cultivated rice seeds.The plant genome · 2022Article
- Anti-viral triterpenes: a review.Phytochemistry reviews : proceedings of the Phytochemical Society of Europe · 2022Review
- Transcriptomic and metabolic analyses reveal the potential mechanism of increasing steroidal alkaloids inFrontiers in plant science · 2022Article
- Representational Difference Analysis of Transcripts Involved in Jervine Biosynthesis.Life (Basel, Switzerland) · 2020Article
- Genome-Wide HMG Family Investigation and Its Role in Glycoalkaloid Accumulation in Wild Tuber-BearingLife (Basel, Switzerland) · 2020Article
- Characterization and Function of 3-Hydroxy-3-Methylglutaryl-CoA Reductase inFrontiers in plant science · 2019Article
- The mevalonate pathway but not the methylerythritol phosphate pathway is critical for elaioplast and pollen coat development inPlant biotechnology (Tokyo, Japan) · 2018Article
- Transcriptome analysis reveals in vitro-cultured regeneration bulbs as a promising source for targeted3 Biotech · 2018Article
- Lanosterol synthase-like is involved with differential accumulation of steroidal glycoalkaloids in potato.Planta · 2017Article
- Molecular cloning and differential expression analysis of a squalene synthase gene from Dioscorea zingiberensis, an important pharmaceutical plant.Molecular biology reports · 2014Article
- The Plant Membrane-Associated REMORIN1.3 Accumulates in Discrete Perihaustorial Domains and Enhances Susceptibility to Phytophthora infestans.Plant physiology · 2014Article
- Sterol-dependent induction of plant defense responses by a microbe-associated molecular pattern from Trichoderma viride.Plant physiology · 2014Article
- Sequence diversity in coding regions of candidate genes in the glycoalkaloid biosynthetic pathway of wild potato species.G3 (Bethesda, Md.) · 2013Article
- Lipid transport between the endoplasmic reticulum and mitochondria.Cold Spring Harbor perspectives in biology · 2013Review
- Cloning and functional characterization of 3-hydroxy-3-methylglutaryl coenzyme A reductase gene from Withania somnifera: an important medicinal plant.Protoplasma · 2013Article
- Article
- Roles for farnesol and ABA in Arabidopsis flower development.Plant signaling & behavior · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sterols, which are biosynthesized via the cytoplasmic mevalonate (MVA) pathway, are important structural components of the plasma membrane and precursors of steroid hormones in both vertebrates and plants. Ergosterol and cholesterol are the major sterols in yeast and vertebrates, respectively. In contrast, plants produce a wide variety of phytosterols, which have various functions in plant development. Although the general biosynthetic pathway to plant sterols has been defined, the details of the biochemical, physiological, and developmental functions of genes involved in the biosynthetic network and their regulation are not well understood. Molecular genetic analyses are an effective approach to use when studying these fascinating problems. Since three enzymes, 3-hydroxy-3-methylglutaryl CoA reductase, farnesyl diphosphate synthase, and lanosterol synthase, have been functionally characterized in planta, we reviewed recent progress on these enzymes. Arabidopsis T-DNA and transposon insertion mutants are now widely available. The use of molecular genetics, molecular biology, and bioorganic chemical approaches on these mutants, as well as inhibitors of the MVA pathway, should help us to understand plant sterol biosynthesis comprehensively.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.