ReviewMolecular pain2007
Techniques for assessing knee joint pain in arthritis.
Review in Molecular pain, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 81 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
81 citing papers in PubMed, 177 citations in OpenAlex.
- Short-term efficacy of calcium fructoborate on subjects with knee discomfort: a comparative, double-blind, placebo-controlled clinical study.Clinical interventions in aging · 2014Trial
- A Review of Rodent Behavior, Mobility, and Pain Modifications in Response to Destabilization of the Medial Meniscus Injury.Biomedicines · 2025Review
- Impaired amygdala astrocytic signaling worsens neuropathic pain-associated neuronal functions and behaviors.Frontiers in pharmacology · 2024Article
- Translational evaluation of gait behavior in rodent models of arthritic disorders with the CatWalk device - a narrative review.Frontiers in medicine · 2023Review
- Localized Multi-Site Knee Bioimpedance as a Predictor for Knee Osteoarthritis Associated Pain Within Older Adults During Free-Living.IEEE open journal of engineering in medicine and biology · 2023Article
- An Insight on the Biomedical Potential of Portuguese Propolis from Gerês.Foods (Basel, Switzerland) · 2022Article
- Fatty-Acid-RichMolecules (Basel, Switzerland) · 2022Article
- Optogenetic manipulations of CeA-CRF neurons modulate pain- and anxiety-like behaviors in neuropathic pain and control rats.Neuropharmacology · 2022Article
- Spontaneous pain as a challenge of research and management in chronic pain.Medical review (2021) · 2022Review
- Mouse Models of Osteoarthritis: A Summary of Models and Outcomes Assessment.Comparative medicine · 2022Review
- Gingerol-Enriched Ginger Supplementation Mitigates Neuropathic PainFrontiers in pharmacology · 2022Article
- Zingerone (4-(four-hydroxy-3-methylphenyl) butane-two-1) modulates adjuvant-induced rheumatoid arthritis by regulating inflammatory cytokines and antioxidants.Redox report : communications in free radical research · 2021Article
- Fear Extinction-Based Inter-Individual and Sex Differences in Pain-Related Vocalizations and Anxiety-like Behaviors but Not Nocifensive Reflexes.Brain sciences · 2021Article
- The effects of wheel-running using the upper limbs following immobilization after inducing arthritis in the knees of rats.Physiological research · 2021Article
- Kappa opioid receptor activation in the amygdala disinhibits CRF neurons to generate pain-like behaviors.Neuropharmacology · 2021Article
- Optogenetic Manipulations of Amygdala Neurons Modulate Spinal Nociceptive Processing and Behavior Under Normal Conditions and in an Arthritis Pain Model.Frontiers in pharmacology · 2021Article
- Neurobiological aspects of pain in the context of alcohol use disorder.International review of neurobiology · 2021Article
- Article
- Methods for Evaluating Sensory, Affective and Cognitive Disorders in Neuropathic Rodents.Current neuropharmacology · 2021Review
- Zika virus-induced neuro-ocular pathology in immunocompetent mice correlates with anti-ganglioside autoantibodies.Human vaccines & immunotherapeutics · 2020Article
21 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
The assessment of pain is of critical importance for mechanistic studies as well as for the validation of drug targets. This review will focus on knee joint pain associated with arthritis. Different animal models have been developed for the study of knee joint arthritis. Behavioral tests in animal models of knee joint arthritis typically measure knee joint pain rather indirectly. In recent years, however, progress has been made in the development of tests that actually evaluate the sensitivity of the knee joint in arthritis models. They include measurements of the knee extension angle struggle threshold, hind limb withdrawal reflex threshold of knee compression force, and vocalizations in response to stimulation of the knee. A discussion of pain assessment in humans with arthritis pain conditions concludes this review.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.