Evidence map›Paper›PMID 17387633›Full record

ArticleMolecular biology reports2008

Transcriptional inhibition by a non-histone protein from low mobility group in homologous and heterologous in vitro systems.

Maryam Shahhoseini, Azra Rabbani-Chadegani

Abstract read
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In one paragraph

Article in Molecular biology reports, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Maryam ShahhoseiniInstitute of Biochemistry and Biophysics, Department of Biochemistry, University of Tehran, Tehran, P.O. Box 13145-1384, Iran.
Azra Rabbani-Chadegani
University of Tehran · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An acidic non-histone chromosomal protein of low mobility group (LMG) with pI of 5-5.5 and molecular weight of 160 kDa (named LMG160), has been isolated from rat liver nuclei and its inhibitory effect on transcription of DNA in vitro has been detected in a heterologous prokaryotic in vitro transcription system (T7 RNA polymerase) and also confirmed in the homologous cell-free system of rat liver nuclear extract. The results indicate that in the presence of non-histone protein LMG160, in vitro RNA synthesis represses in the both systems, which can suggest a functional role for this non-histone chromosomal protein.

Indexed as

Transcription, GeneticAnimalsCell NucleusChromosomal Proteins, Non-HistoneDNA-Binding ProteinsDNA-Directed RNA PolymerasesElectrophoresis, Agar GelLiver ExtractsRatsViral Proteinsbacteriophage T7 RNA polymeraseChromosomal Proteins, Non-HistoneDNA-Binding ProteinsDNA-Directed RNA PolymerasesLiver Extractslow mobility group protein 160, ratViral Proteins

Identifiers

PMID17387633
OpenAlexW1991745127

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.