ArticleEuropean journal of clinical pharmacology2007
Identification of asthmatic children using prescription data and diagnosis.
Article in European journal of clinical pharmacology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.
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Who cites it
35 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Inter-country variations in anti-asthmatic drug prescriptions for children. Systematic review of studies published during the 2000-2009 period.European journal of clinical pharmacology · 2010Pooled it
- Developing an algorithm to identify people with Chronic Obstructive Pulmonary Disease (COPD) using administrative data.BMC medical informatics and decision making · 2012Trial
- Neonatal vitamin D status and asthma risk after age 5 years: A Danish population-based cohort study.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2026Article
- Trends in childhood asthma in Denmark, Finland, Norway and Sweden.Acta paediatrica (Oslo, Norway : 1992) · 2025Article
- Increased risk of obstructive lung disease in inflammatory bowel disease: A population-based cohort study.United European gastroenterology journal · 2024Article
- No associations between type 1 diabetes and atopic dermatitis, allergic rhinitis, or asthma in childhood: a nationwide Danish case-cohort study.Scientific reports · 2023Article
- Postoperative epilepsy and survival in glioma patients: a nationwide population-based cohort study from 2009 to 2018.Journal of neuro-oncology · 2022Article
- Analysis of the Consumption of Drugs Prescribed for the Treatment of Asthma in Belgian Children.International journal of environmental research and public health · 2022Article
- General Practitioner Attendance in Proximity to HPV Vaccination: A Nationwide, Register-Based, Matched Case-Control Study.Clinical epidemiology · 2020Article
- Validity of asthma diagnoses and patterns of anti-asthmatic drug use in a cohort of 2053 Danish children.Health science reports · 2018Article
- Spirometry monitoring in asthmatic children in Lombardy Region, Italy.BMJ paediatrics open · 2018Article
- Article
- Trends in Antibiotic Use by Birth Season and Birth Year.Pediatrics · 2017Article
- Validation of asthma recording in electronic health records: a systematic review.Clinical epidemiology · 2017Review
- Maternal body mass index before pregnancy is associated with increased bronchodilator dispensing in early childhood: A cross-sectional study.Pediatric pulmonology · 2016Article
- Identification of Dutch children diagnosed with atopic diseases using prescription data: a validation study.European journal of clinical pharmacology · 2016Article
- Identifying patients with asthma in primary care electronic medical record systems Chart analysis-based electronic algorithm validation study.Canadian family physician Medecin de famille canadien · 2015Article
- Prematurity and prescription asthma medication from childhood to young adulthood: a Danish national cohort study.PloS one · 2015Article
- Maternal concentrations of persistent organochlorine pollutants and the risk of asthma in offspring: results from a prospective cohort with 20 years of follow-up.Environmental health perspectives · 2014Article
- Vitamin D intake in mid-pregnancy and child allergic disease - a prospective study in 44,825 Danish mother-child pairs.BMC pregnancy and childbirth · 2013Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe aim of the study was to develop and validate a method for identifying asthmatic children between 6 and 14 years of age based on prescription data on anti-asthmatic drugs and diagnostic data.
methodsA register-based study of 125,907 Danish children aged 6-14 years identified 9695 children who had redeemed at least one anti-asthmatic drug prescription in 2002. The asthma diagnosis in these children was validated by discharge information and by a questionnaire completed by general practitioners. Models based on combinations of different types of drugs were tested to find the best model that would include as many children as possible with a validated diagnosis and exclude as many false positives as possible. Different time windows were tested in terms of detecting the children and the observation period of refilling prescriptions.
resultsThe highest specificity of 0.86 [95% confidence interval (95% CI): 0.84-0.87] together with a sensitivity of 0.63 (95% CI: 0.62-0.65) were found in the model that included children who had redeemed a prescription for any anti-asthmatic drug - with the exception of prescriptions for beta2-agonists as liquid, one prescription only of inhaled beta2-agonist or an inhaled steroid - during a 12-month period. Lengthening the observation time by 6 months did not significantly improve the specificity (0.87; 95% CI: 0.85-0.88), but it did result in a statistically significantly lower sensitivity (0.59; 95% CI: 0.58-0.60).
conclusionRegister-based data on redeemed prescriptions can be utilised to identify asthmatic school children. This method will be useful in health services research and in the proactive care of asthmatic children.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.