Evidence map›Paper›PMID 17386257›Full record

ArticleMolecular cell2007

On again, off again: the SRC-3 transcriptional coactivator moonlights as a translational corepressor.

Paul Anderson, Nancy Kedersha

Open access · bronzeAbstract readComment
PubMed Publisher
In one paragraph

Article in Molecular cell, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.5field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Electrochemical Measurements Reveal Reactive Oxygen Species in Stress Granules*.Angewandte Chemie (International ed. in English) · 2021
    Article
  2. Molecular mechanisms of stress granule assembly and disassembly.Biochimica et biophysica acta. Molecular cell research · 2021
    Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Paul AndersonDivision of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital and Harvard Medical School, Smith 652, One Jimmy Fund Way, Boston, MA 02115, USA.
Nancy Kedersha
Brigham and Women's Hospital · US

Funding

Characterization of mammalian stress granulesR56AI033600 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI ANDERSON, PAUL J. · 2005 to 2005
$437k
NIAID NIH HHS R56 AI033600
6 · The paper itself

Abstract

In a recent issue of Molecular Cell, Yu et al. (2007) reported that the steroid receptor coactivator-3 (SRC-3) has a novel cytoplasmic function: it activates the translational silencers TIA-1 and TIAR and thus inhibits the translation of proinflammatory cytokines.

Indexed as

Protein BiosynthesisTranscription, GeneticAnimalsCell NucleusHistone AcetyltransferasesHumansNuclear Receptor Coactivator 3RNA, MessengerTrans-ActivatorsTumor Necrosis Factor-alphaHistone AcetyltransferasesNCOA3 protein, humanNuclear Receptor Coactivator 3RNA, MessengerTrans-ActivatorsTumor Necrosis Factor-alpha

Identifiers

PMID17386257
OpenAlexW2002564816

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.