ArticleJournal of bacteriology2007
Transcription of all amoC copies is associated with recovery of Nitrosomonas europaea from ammonia starvation.
Article in Journal of bacteriology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 48 citations in OpenAlex.
- Ammonia oxidation and recalcitrant carbon degradation fuel mixotrophic growth in the symbiont community of a deep-sea sponge.Microbiome · 2026Article
- Ammonia monooxygenase: a work in progress.Chemical science · 2026Review
- Multi-omics provides functional insights and underscores practical challenges in assessing the composition and performance of a nitrifying microbial consortium.Applied and environmental microbiology · 2026Article
- Article
- Growth of soil ammonia-oxidizing archaea on air-exposed solid surface.ISME communications · 2024Article
- Role of Nitric Oxide in Hydroxylamine Oxidation by Ammonia-Oxidizing Bacteria.Applied and environmental microbiology · 2023Article
- Unexpected complexity of the ammonia monooxygenase in archaea.The ISME journal · 2023Article
- Large freshwater phages with the potential to augment aerobic methane oxidation.Nature microbiology · 2020Article
- Article
- Genomic Insights of "Frontiers in microbiology · 2020Article
- Stress response of a marine ammonia-oxidizing archaeon informs physiological status of environmental populations.The ISME journal · 2018Article
- Ammonia-Oxidizing Archaea and Bacteria Differentially Contribute to Ammonia Oxidation in Sediments from Adjacent Waters of Rushan Bay, China.Frontiers in microbiology · 2018Article
- Evolutionary History of Copper Membrane Monooxygenases.Frontiers in microbiology · 2018Article
- Proteomics and comparative genomics of Nitrososphaera viennensis reveal the core genome and adaptations of archaeal ammonia oxidizers.Proceedings of the National Academy of Sciences of the United States of America · 2016Article
- Engineering of Nitrosomonas europaea to express Vitreoscilla hemoglobin enhances oxygen uptake and conversion of ammonia to nitrite.AMB Express · 2015Article
- Transcriptional response of the archaeal ammonia oxidizer Nitrosopumilus maritimus to low and environmentally relevant ammonia concentrations.Applied and environmental microbiology · 2013Article
- Application of an integrated statistical design for optimization of culture condition for ammonium removal by Nitrosomonas europaea.PloS one · 2013Article
- Diversity, physiology, and niche differentiation of ammonia-oxidizing archaea.Applied and environmental microbiology · 2012Review
- Dynamics of ammonia-oxidizing archaea and bacteria populations and contributions to soil nitrification potentials.The ISME journal · 2012Article
- The divergent AmoC3 subunit of ammonia monooxygenase functions as part of a stress response system in Nitrosomonas europaea.Journal of bacteriology · 2012Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The chemolithotrophic ammonia-oxidizing bacterium Nitrosomonas europaea is known to be highly resistant to starvation conditions. The transcriptional response of N. europaea to ammonia addition following short- and long-term starvation was examined by primer extension and S1 nuclease protection analyses of genes encoding enzymes for ammonia oxidation (amoCAB operons) and CO(2) fixation (cbbLS), a third, lone copy of amoC (amoC(3)), and two representative housekeeping genes (glyA and rpsJ). Primer extension analysis of RNA isolated from growing, starved, and recovering cells revealed two differentially regulated promoters upstream of the two amoCAB operons. The distal sigma(70) type amoCAB promoter was constitutively active in the presence of ammonia, but the proximal promoter was only active when cells were recovering from ammonia starvation. The lone, divergent copy of amoC (amoC(3)) was expressed only during recovery. Both the proximal amoC(1,2) promoter and the amoC(3) promoter are similar to gram-negative sigma(E) promoters, thus implicating sigma(E) in the regulation of the recovery response. Although modeling of subunit interactions suggested that a nonconservative proline substitution in AmoC(3) may modify the activity of the holoenzyme, characterization of a DeltaamoC(3) strain showed no significant difference in starvation recovery under conditions evaluated. In contrast to the amo transcripts, a delayed appearance of transcripts for a gene required for CO(2) fixation (cbbL) suggested that its transcription is retarded until sufficient energy is available. Overall, these data revealed a programmed exit from starvation likely involving regulation by sigma(E) and the coordinated regulation of catabolic and anabolic genes.
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