ArticleProceedings of the National Academy of Sciences of the United States of America2007
Meiotic recombination-related DNA synthesis and its implications for cross-over and non-cross-over recombinant formation.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
31 citing papers in PubMed, 55 citations in OpenAlex.
- Recombination-coupled DNA synthesis facilitates post-invasion steps in meiotic crossover and noncrossover formations.Nucleic acids research · 2025Article
- Meiotic double-strand break repair DNA synthesis tracts in Arabidopsis thaliana.PLoS genetics · 2024Article
- Meiosis through three centuries.Chromosoma · 2024Review
- Evolution of crossover interference enables stable autopolyploidy by ensuring pairwise partner connections in Arabidopsis arenosa.Current biology : CB · 2021Article
- Timing of appearance of new mutations during yeast meiosis and their association with recombination.Current genetics · 2020Article
- Refined spatial temporal epigenomic profiling reveals intrinsic connection between PRDM9-mediated H3K4me3 and the fate of double-stranded breaks.Cell research · 2020Article
- Recruitment of Rec8, Pds5 and Rad61/Wapl to meiotic homolog pairing, recombination, axis formation and S-phase.Nucleic acids research · 2019Article
- The Largest Subunit of DNA Polymerase Delta Is Required for Normal Formation of Meiotic Type I Crossovers.Plant physiology · 2019Article
- Modulating Crossover Frequency and Interference for Obligate Crossovers inG3 (Bethesda, Md.) · 2017Article
- The MRX Complex Ensures NHEJ Fidelity through Multiple Pathways Including Xrs2-FHA-Dependent Tel1 Activation.PLoS genetics · 2016Article
- Meiotic Recombination: The Essence of Heredity.Cold Spring Harbor perspectives in biology · 2015Review
- Formation of interference-sensitive meiotic cross-overs requires sufficient DNA leading-strand elongation.Proceedings of the National Academy of Sciences of the United States of America · 2015Article
- Recombination, Pairing, and Synapsis of Homologs during Meiosis.Cold Spring Harbor perspectives in biology · 2015Review
- Interference-mediated synaptonemal complex formation with embedded crossover designation.Proceedings of the National Academy of Sciences of the United States of America · 2014Article
- Article
- PCNA is efficiently loaded on the DNA recombination intermediate to modulate polymerase δ, η, and ζ activities.Proceedings of the National Academy of Sciences of the United States of America · 2013Article
- Trans-Lesion DNA Polymerases May Be Involved in Yeast Meiosis.G3 (Bethesda, Md.) · 2013Article
- Mouse HFM1/Mer3 is required for crossover formation and complete synapsis of homologous chromosomes during meiosis.PLoS genetics · 2013Article
- High-resolution genotyping and mapping of recombination and gene conversion in the protozoan Theileria parva using whole genome sequencing.BMC genomics · 2012Article
- The DNA replication factor RFC1 is required for interference-sensitive meiotic crossovers in Arabidopsis thaliana.PLoS genetics · 2012Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
Abstract
Meiotic recombination-related DNA synthesis (MRDS) was analyzed in Saccharomyces cerevisiae by specifically timed incorporation of thymidine analogs into chromosomes. Lengths and positions of incorporation tracts were determined relative to a known recombination hot spot along DNA, as was the timing and localization of incorporation relative to forming and formed synaptonemal complex in spread chromosomes. Distinct patterns could be specifically associated with the majority cross-over and non-cross-over recombination processes. The results obtained provide direct evidence for key aspects of current consensus recombination models, provide information regarding temporal and spatial relationships between non-cross-over formation and the synaptonemal complex, and raise the possibility that removal of RecA homolog Rad51 plays a key role in regulating onset of MRDS. Finally, classical observations on MRDS in Drosophila, mouse, and lily are readily mapped onto the findings presented here, providing further evidence for a broadly conserved meiotic recombination process.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.