ArticleCell2007
Argonautes and company: sailing against the wind.
Article in Cell, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 32 citations in OpenAlex.
- tRF-33-P4R8YP9LON4VDP inhibits gastric cancer progression via modulating STAT3 signaling pathway in an AGO2-dependent manner.Oncogene · 2024Article
- Article
- tRF3008A suppresses the progression and metastasis of colorectal cancer by destabilizing FOXK1 in an AGO-dependent manner.Journal of experimental & clinical cancer research : CR · 2022Article
- Argonaute-miRNA Complexes Silence Target mRNAs in the Nucleus of Mammalian Stem Cells.Molecular cell · 2018Article
- Tubby-like protein 1 (Tulp1) is a target of microRNA-134 and is down-regulated in experimental epilepsy.International journal of physiology, pathophysiology and pharmacology · 2017Article
- Dysregulated RNA-Induced Silencing Complex (RISC) Assembly within CNS Corresponds with Abnormal miRNA Expression during Autoimmune Demyelination.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2015Article
- Article
- Argonaute 2 in cell-secreted microvesicles guides the function of secreted miRNAs in recipient cells.PloS one · 2014Article
- Mechanisms of miRNA-Mediated Gene Regulation from Common Downregulation to mRNA-Specific Upregulation.International journal of genomics · 2014Review
- Barcoded cDNA library preparation for small RNA profiling by next-generation sequencing.Methods (San Diego, Calif.) · 2012Article
- Atomistic mechanism of microRNA translation upregulation via molecular dynamics simulations.PloS one · 2012Article
- RNA-ligase-dependent biases in miRNA representation in deep-sequenced small RNA cDNA libraries.RNA (New York, N.Y.) · 2011Article
- Regulation of erythroid differentiation by miR-376a and its targets.Cell research · 2011Article
- Essential role of the RNA-binding protein HuR in progenitor cell survival in mice.The Journal of clinical investigation · 2009Article
- The RNA-binding protein Elavl1/HuR is essential for placental branching morphogenesis and embryonic development.Molecular and cellular biology · 2009Article
- Role of siRNAs and miRNAs in the processes of RNA-mediated gene silencing during viral infections.Cytology and genetics · 2009Review
- Review
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The 3'-untranslated region (UTR) of mRNA is crucial for posttranscriptional regulation. In this issue, Vasudevan and Steitz (2007) report a new function for AGO2 and FXR1--two proteins that have been linked to the regulation of microRNAs and translation repression. AGO2 and FXR1 bind to the AU-rich element in the 3'-UTR of TNFalpha mRNA, unexpectedly activating its translation in a cell growth-dependent manner.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.