Evidence map›Paper›PMID 17382566›Full record

ReviewSeminars in cell & developmental biology2007

Mammary glands and feathers: comparing two skin appendages which help define novel classes during vertebrate evolution.

Randall B Widelitz, Jacqueline M Veltmaat, Julie Ann Mayer, John Foley, Cheng-Ming Chuong

Abstract readReview
In one paragraph

Review in Seminars in cell & developmental biology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 41 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. A shark-inspired general model of tooth morphogenesis unveils developmental asymmetries in phenotype transitions.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. The "tao" of integuments.Science (New York, N.Y.) · 2016
    Article
  16. Article
  17. Article
  18. Review
  19. Development, regeneration, and evolution of feathers.Annual review of animal biosciences · 2015
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Randall B WidelitzDepartment of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA. widelitz@usc.edu
Jacqueline M Veltmaat
Julie Ann Mayer
John Foley
Cheng-Ming Chuong
University of Southern California · USIndiana University School of MedicineInstitute of Molecular and Cell Biology · SG

Funding

Size regulation of skin appendagesR01AR047364 · NIAMS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Cheng-Ming Chuong · 2002 to 2026
$10.1M
LIW5R01AR042177 · NIAMS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI CHUONG, CHENG-MING · 1995 to 2013
$5.7M
REGULATION OF EPIDERMAL DIFFERENTATION BY PTHRPR01AR045585 · NIAMS · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI FOLEY, JOHN GREGORY · 2000 to 2004
$1.4M
Sex Hormone Regulation of Organ FormationR01AR052397 · NIAMS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI WIDELITZ, RANDALL BRUCE · 2006 to 2008
$749k
Local Regulation Of Calcium Release In Skeletal MuscleK01AR002177 · NIAMS · UNIVERSITY OF MARYLAND BALTIMORE · PI WARD, CHRISTOPHER WILLIAM · 2001 to 2005
$647k
NIAMS NIH HHS AR052397NIAMS NIH HHS AR2177NIAMS NIH HHS AR45585NIAMS NIH HHS AR47364NIAMS NIH HHS K01 AR002177NIAMS NIH HHS R01 AR042177NIAMS NIH HHS R01 AR045585NIAMS NIH HHS R01 AR047364NIAMS NIH HHS R01 AR052397
6 · The paper itself

Abstract

It may appear counter-intuitive to compare feathers and mammary glands. However, through this Evo-Devo analysis, we appreciate how species interact with the environment, requiring different ectodermal organs. Novel ectodermal organs help define evolutionary directions, leading to new organism classes as exemplified by feathers for Aves and mammary glands for Mammals. Here, we review their structure, function, morphogenesis and regenerative cycling. Interestingly, both organs undergo extensive branching for different reasons; feather branching is driven by mechanical advantage while mammary glands nourish young. Besides natural selection, both are regulated by sex hormones and acquired a secondary function for attracting mates, contributing to sexual selection.

Indexed as

Biological EvolutionAnimalsFeathersHumansIntegumentary SystemMammary Glands, HumanModels, BiologicalVertebrates

Identifiers

PMID17382566
PMCPMC4382004
OpenAlexW2084079837

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.